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BACSU:MCCA

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Species (Taxon ID) Bacillus subtilis (strain 168). (224308)
Gene Name(s) mccA (synonyms: yrhA)
Protein Name(s) O-acetylserine dependent cystathionine beta-synthase
External Links
UniProt O05393
EMBL U93874
AL009126
PIR H69973
RefSeq NP_390604.1
ProteinModelPortal O05393
SMR O05393
STRING 224308.BSU27260
PaxDb O05393
EnsemblBacteria CAB14668
GeneID 937576
KEGG bsu:BSU27260
PATRIC 18977308
GenoList BSU27260
eggNOG COG0031
HOGENOM HOG000217394
InParanoid O05393
KO K17216
OMA MSKEIFN
OrthoDB EOG6Q2SP8
PhylomeDB O05393
BioCyc BSUB:BSU27260-MONOMER
Proteomes UP000001570
GO GO:0016829
GO:0006535
InterPro IPR001216
IPR001926
Pfam PF00291
SUPFAM SSF53686
PROSITE PS00901

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004122

PMID:17056751[1]

ECO:0000315

Figure 4 shows that when a mutant strain with a deletion of the yrhA gene was compared to the wild type strain growth was significantly decreased. Indication that methionine utilization mostly requires the yhrA gene for normal growth.

complete
CACAO 4311

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:17056751[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006535

cysteine biosynthetic process from serine

PMID:17056751[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004124

cysteine synthase activity

PMID:17056751[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004122

cystathionine beta-synthase activity

PMID:17056751[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0030170

pyridoxal phosphate binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10192
PANTHER:PTN000034104
UniProtKB:P35520
UniProtKB:P9WG59
UniProtKB:P9WP53
UniProtKB:P9WP55
UniProtKB:Q79FV4
WB:WBGene00013866

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000034104
SGD:S000003387
UniProtKB:P35520
WB:WBGene00013866

C

Seeded From UniProt

complete

involved_in

GO:0006535

cysteine biosynthetic process from serine

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001216

P

Seeded From UniProt

complete

involved_in

GO:0008652

cellular amino acid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0028

P

Seeded From UniProt

complete

involved_in

GO:0019344

cysteine biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0198

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Hullo, MF et al. (2007) Conversion of methionine to cysteine in Bacillus subtilis and its regulation. J. Bacteriol. 189 187-97 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page