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BACSU:HRCA

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Species (Taxon ID) Bacillus subtilis (strain 168). (224308)
Gene Name(s) hrcA (ECO:0000255 with HAMAP-Rule:MF_00081) (synonyms: yqeS, yqxE)
Protein Name(s) Heat-inducible transcription repressor HrcA (ECO:0000255 with HAMAP-Rule:MF_00081)
External Links
UniProt P25499
EMBL M84964
D84432
AL009126
PIR A41874
RefSeq NP_390427.1
ProteinModelPortal P25499
SMR P25499
IntAct P25499
STRING 224308.BSU25490
PaxDb P25499
EnsemblBacteria CAB14491
GeneID 937843
KEGG bsu:BSU25490
PATRIC 18976936
GenoList BSU25490
eggNOG COG1420
HOGENOM HOG000058933
InParanoid P25499
KO K03705
OMA RNEMSDL
OrthoDB EOG632D4G
PhylomeDB P25499
BioCyc BSUB:BSU25490-MONOMER
Proteomes UP000001570
GO GO:0003677
GO:0045892
GO:0006351
Gene3D 1.10.10.10
3.30.450.40
HAMAP MF_00081
InterPro IPR029016
IPR002571
IPR021153
IPR011991
Pfam PF01628
PIRSF PIRSF005485
SUPFAM SSF55781
TIGRFAMs TIGR00331

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:8576042[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

GO:0045892

negative regulation of transcription, DNA-dependent

PMID:8576042[1]

ECO:0000315

P

As can be seen from Fig. 1A, lane 4, in the DhrcA mutant,the grpE gene is expressed at a significantly higher level than that of the wild-type strain (lane 1), and there is no further increase in the amount of grpE-specific transcript after temperature upshift.

We conclude from these results that it is hrcA rather than grpE which codes for a negative regulator of class I heat shock genes.

complete
CACAO 2634

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002165771
UniProtKB:P25499
UniProtKB:P9WMK3

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002571
InterPro:IPR021153

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002571
InterPro:IPR021153

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000001251

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Schulz, A & Schumann, W (1996) hrcA, the first gene of the Bacillus subtilis dnaK operon encodes a negative regulator of class I heat shock genes. J. Bacteriol. 178 1088-93 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page