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BACSU:HIUH

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Species (Taxon ID) Bacillus subtilis (strain 168). (224308)
Gene Name(s) pucM (synonyms: yunM)
Protein Name(s) 5-hydroxyisourate hydrolase

HIU hydrolase HIUHase Transthyretin-related protein TRP

External Links
UniProt O32142
EMBL AL009126
PIR H70016
RefSeq NP_391126.2
PDB 2H0E
2H0F
2H0J
PDBsum 2H0E
2H0F
2H0J
ProteinModelPortal O32142
SMR O32142
STRING 224308.BSU32460
TCDB 9.B.35.2.1
PaxDb O32142
EnsemblBacteria CAB15236
GeneID 937977
KEGG bsu:BSU32460
PATRIC 18978464
GenoList BSU32460
eggNOG COG2351
HOGENOM HOG000251776
InParanoid O32142
KO K07127
OMA KFSTHIL
OrthoDB EOG6038XF
PhylomeDB O32142
BioCyc BSUB:BSU32460-MONOMER
UniPathway UPA00394
EvolutionaryTrace O32142
Proteomes UP000001570
GO GO:0033971
GO:0006144
GO:0006810
GO:0019628
Gene3D 2.60.40.180
InterPro IPR014306
IPR023418
IPR000895
IPR023416
IPR023419
Pfam PF00576
PRINTS PR00189
SUPFAM SSF49472
TIGRFAMs TIGR02962
PROSITE PS00768
PS00769

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016787

hydrolase activity

PMID:16782815[1]

ECO:0000315

F

Figure 5: Using absorbance, various PucM mutants were analyzed and compared by their ability to hydrolyze 5-hydroxyisourate (HIU)relative to time.

complete

involved_in

GO:0006144

purine nucleobase metabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000044586
ZFIN:ZDB-GENE-060825-253

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:16782815[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:O32142

F

Seeded From UniProt

complete

involved_in

GO:0006144

purine nucleobase metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014306

P

Seeded From UniProt

complete

enables

GO:0033971

hydroxyisourate hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014306

F

Seeded From UniProt

complete

enables

GO:0033971

hydroxyisourate hydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.2.17

F

Seeded From UniProt

complete

involved_in

GO:0006144

purine nucleobase metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0659

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0019628

urate catabolic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00394

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Jung, DK et al. (2006) Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of the transthyretin-related protein family. Proc. Natl. Acad. Sci. U.S.A. 103 9790-5 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page