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BACSU:GLOX
Contents
| Species (Taxon ID) | Bacillus subtilis (strain 168). (224308) | |
| Gene Name(s) | thiO (synonyms: goxB, yjbR) | |
| Protein Name(s) | Glycine oxidase
GO | |
| External Links | ||
| UniProt | O31616 | |
| EMBL | AL009126 | |
| PIR | B69845 | |
| RefSeq | NP_389049.1 WP_003245044.1 | |
| PDB | 1NG3 1NG4 1RYI 3IF9 | |
| PDBsum | 1NG3 1NG4 1RYI 3IF9 | |
| ProteinModelPortal | O31616 | |
| SMR | O31616 | |
| STRING | 224308.Bsubs1_010100006451 | |
| DrugBank | DB02713 DB03147 DB03085 | |
| PaxDb | O31616 | |
| EnsemblBacteria | CAB13024 | |
| GeneID | 939377 | |
| KEGG | bsu:BSU11670 | |
| PATRIC | 18974051 | |
| eggNOG | COG0665 | |
| HOGENOM | HOG000042039 | |
| InParanoid | O31616 | |
| KO | K03153 | |
| OMA | CTPDLKP | |
| PhylomeDB | O31616 | |
| BioCyc | BSUB:BSU11670-MONOMER MetaCyc:BSU11670-MONOMER | |
| BRENDA | 1.4.3.19 | |
| SABIO-RK | O31616 | |
| UniPathway | UPA00060 | |
| EvolutionaryTrace | O31616 | |
| Proteomes | UP000001570 | |
| GO | GO:0005737 GO:0050660 GO:0043799 GO:0016491 GO:0009635 GO:0009228 GO:0009229 | |
| Gene3D | 3.50.50.60 | |
| InterPro | IPR006076 IPR023753 IPR012727 | |
| Pfam | PF01266 | |
| SUPFAM | SSF51905 | |
| TIGRFAMs | TIGR02352 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
Contributes to |
GO:0043799 |
sarcosine oxidase activity |
ECO:0000250 |
|
F |
After finding a gene product termed yjbR they noticed that it had a sequence similarity with bacteria sarcosine oxidases. From there they measured yjbR gene products substrate specificity (table 2). They found that there is higher rate of activites with N-methyl-d-alanine, d-proline, d-alanine, and d-2-aminobutyrate. |
complete | |||
|
involved_in |
GO:0006520 |
cellular amino acid metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0071949 |
FAD binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043799 |
glycine oxidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009228 |
thiamine biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11822 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000354057 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043799 |
glycine oxidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009635 |
response to herbicide |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009228 |
thiamine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009229 |
thiamine diphosphate biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00060 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Nishiya, Y & Imanaka, T (1998) Purification and characterization of a novel glycine oxidase from Bacillus subtilis. FEBS Lett. 438 263-6 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Job, V et al. (2002) Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein. J. Biol. Chem. 277 6985-93 PubMed GONUTS page
- ↑ Settembre, EC et al. (2003) Structural and mechanistic studies on ThiO, a glycine oxidase essential for thiamin biosynthesis in Bacillus subtilis. Biochemistry 42 2971-81 PubMed GONUTS page
- ↑ 4.0 4.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
