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BACSU:DESK
Contents
Species (Taxon ID) | Bacillus subtilis (strain 168). (224308) | |
Gene Name(s) | desK (synonyms: yocF) | |
Protein Name(s) | Sensor histidine kinase DesK | |
External Links | ||
UniProt | O34757 | |
EMBL | AF027868 AL009126 | |
PIR | C69901 | |
RefSeq | NP_389800.1 WP_003231271.1 | |
PDB | 3EHF 3EHG 3EHH 3EHJ 3GIE 3GIF 3GIG | |
PDBsum | 3EHF 3EHG 3EHH 3EHJ 3GIE 3GIF 3GIG | |
ProteinModelPortal | O34757 | |
SMR | O34757 | |
DIP | DIP-48966N | |
STRING | 224308.BSU19190 | |
PaxDb | O34757 | |
DNASU | 939678 | |
EnsemblBacteria | CAB13811 | |
GeneID | 939678 | |
KEGG | bsu:BSU19190 | |
PATRIC | 18975687 | |
GenoList | BSU19190 | |
eggNOG | COG4585 | |
HOGENOM | HOG000019645 | |
InParanoid | O34757 | |
KO | K07778 | |
OMA | HAHEVRI | |
OrthoDB | EOG6W9X4M | |
PhylomeDB | O34757 | |
BioCyc | BSUB:BSU19190-MONOMER | |
EvolutionaryTrace | O34757 | |
Proteomes | UP000001570 | |
GO | GO:0016021 GO:0005886 GO:0005524 GO:0004721 GO:0000155 GO:0016311 | |
Gene3D | 3.30.565.10 | |
InterPro | IPR003594 IPR011712 | |
Pfam | PF02518 PF07730 | |
SMART | SM00387 | |
SUPFAM | SSF55874 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000314 |
F |
Fig. 3 A shows DesKC phosphatase activity |
complete | |||||
GO:0004672 |
protein kinase activity |
ECO:0000314 |
F |
Fig. 4A The left image shows kinase activity at time intervals at both 25C (top) and 37C (bottom). Kinase activity was up-regulated at lower temperature |
complete | |||||
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006470 |
protein dephosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004721 |
P |
Seeded From UniProt |
complete | ||
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000314 |
F |
Fig. 4B Left figure show phosphatase activity of desK at 25C (top) and 37C (bottom). |
complete | |||||
involved_in |
GO:0018106 |
peptidyl-histidine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004673 |
P |
Seeded From UniProt |
complete | ||
GO:0016740 |
transferase activity |
ECO:0000314 |
F |
Fig. 4C Figure on the left show phosphotransferase activity of desK at 25C (top) and 37C (bottom). |
complete | |||||
involved_in |
GO:0023014 |
signal transduction by protein phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0000155 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0000155 |
phosphorelay sensor kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000160 |
phosphorelay signal transduction system |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0046983 |
protein dimerization activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004673 |
protein histidine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000160 |
phosphorelay signal transduction system |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Albanesi, D et al. (2004) The membrane fluidity sensor DesK of Bacillus subtilis controls the signal decay of its cognate response regulator. J. Bacteriol. 186 2655-63 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Albanesi, D et al. (2009) Structural plasticity and catalysis regulation of a thermosensor histidine kinase. Proc. Natl. Acad. Sci. U.S.A. 106 16185-90 PubMed GONUTS page
p
- GO:0018106 ! peptidyl-histidine phosphorylation
- GO:0004721 ! phosphoprotein phosphatase activity
- GO:0000160 ! phosphorelay signal transduction system
- GO:0000155 ! phosphorelay sensor kinase activity
- GO:0016310 ! phosphorylation
- GO:0005886 ! plasma membrane
- GO:0006470 ! protein dephosphorylation
- GO:0046983 ! protein dimerization activity
- GO:0004673 ! protein histidine kinase activity
- GO:0004672 ! protein kinase activity