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BACSU:DACA
Contents
| Species (Taxon ID) | Bacillus subtilis (strain 168). (224308) | |
| Gene Name(s) | dacA | |
| Protein Name(s) | D-alanyl-D-alanine carboxypeptidase DacA
CPase DD-carboxypeptidase DD-peptidase Penicillin-binding protein 5 PBP-5 | |
| External Links | ||
| UniProt | P08750 | |
| EMBL | D26185 AL009126 M13766 | |
| PIR | S66040 | |
| RefSeq | NP_387891.1 | |
| ProteinModelPortal | P08750 | |
| SMR | P08750 | |
| STRING | 224308.BSU00100 | |
| ChEMBL | CHEMBL3112381 | |
| MEROPS | S11.001 | |
| PaxDb | P08750 | |
| EnsemblBacteria | CAB11786 | |
| GeneID | 940000 | |
| KEGG | bsu:BSU00100 | |
| PATRIC | 18971479 | |
| GenoList | BSU00100 | |
| eggNOG | COG1686 | |
| HOGENOM | HOG000086625 | |
| InParanoid | P08750 | |
| KO | K07258 | |
| OMA | LACSIFM | |
| OrthoDB | EOG657JCD | |
| PhylomeDB | P08750 | |
| BioCyc | BSUB:BSU00100-MONOMER | |
| UniPathway | UPA00219 | |
| Proteomes | UP000001570 | |
| GO | GO:0005618 GO:0005576 GO:0009002 GO:0071555 GO:0009252 GO:0008360 | |
| Gene3D | 2.60.410.10 3.40.710.10 | |
| InterPro | IPR012338 IPR015956 IPR018044 IPR012907 IPR001967 | |
| Pfam | PF07943 PF00768 | |
| PRINTS | PR00725 | |
| SMART | SM00936 | |
| SUPFAM | SSF56601 SSF69189 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0009002 |
serine-type D-Ala-D-Ala carboxypeptidase activity |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004175 |
endopeptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG12015 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004180 |
carboxypeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
| GO:0009002 |
serine-type D-Ala-D-Ala carboxypeptidase activity |
ECO:0000247 |
|
F |
There are several regions of similarity between the amino acid sequences of B. subtilis PBP 5 and E. coli PBP 5 (4) (Fig. 2), accounting for an overall 25% identity. This suggests (8) that these proteins are homologous. The similar regions (Fig. 2) include one around the active-site serine residues (positions 36 and 44 for B. subtilis and E. coli, respectively), extending from positions 7 to 56 in B. subtilis PBP 5 (47% identical amino acids). |
complete | ||||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001967 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0009002 |
serine-type D-Ala-D-Ala carboxypeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001967 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0009002 |
serine-type D-Ala-D-Ala carboxypeptidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008360 |
regulation of cell shape |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071555 |
cell wall organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004180 |
carboxypeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009252 |
peptidoglycan biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0573 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Todd, JA et al. (1986) Reduced heat resistance of mutant spores after cloning and mutagenesis of the Bacillus subtilis gene encoding penicillin-binding protein 5. J. Bacteriol. 167 257-64 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
