BACSU:AHPC

Species (Taxon ID)	Bacillus subtilis (strain 168). (224308)
Gene Name(s)	ahpC
Protein Name(s)	Alkyl hydroperoxide reductase subunit C Alkyl hydroperoxide reductase protein C22 General stress protein 22 Peroxiredoxin Thioredoxin peroxidase
External Links
UniProt	P80239
EMBL	D78193 AL009126
PIR	F69583
RefSeq	NP_391889.1
ProteinModelPortal	P80239
SMR	P80239
IntAct	P80239
MINT	MINT-8366060
STRING	224308.BSU40090
PeroxiBase	4904
PaxDb	P80239
EnsemblBacteria	CAB16046
GeneID	938147
KEGG	bsu:BSU40090
PATRIC	18980088
GenoList	BSU40090
eggNOG	COG0450
HOGENOM	HOG000022343
InParanoid	P80239
KO	K03386
OMA	GNVWKEW
OrthoDB	EOG67X1XH
PhylomeDB	P80239
BioCyc	BSUB:BSU40090-MONOMER
Proteomes	UP000001570
GO	GO:0004601 GO:0051920 GO:0006979
Gene3D	3.40.30.10
InterPro	IPR017559 IPR000866 IPR024706 IPR019479 IPR012336
Pfam	PF10417 PF00578
PIRSF	PIRSF000239
SUPFAM	SSF52833
TIGRFAMs	TIGR03137
PROSITE	PS51352

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006950	response to stress	PMID:8932315	ECO:0000315			P		..a katA ahpC double mutant (HB6567 and its derivatives) exhibits slow growth in liquid media and lyses on LB plates. These defects are aggravated by the mrgA mutation in the triple mutant, HB6599. This strain could not grow aerobically (and grew only poorly microaerobically) in our defined minimal medium. Cell viability measurements with rich media confirm that katA ahpC (HB6567) and katA ahpC mrgA (HB6599)mutants are most compromised in aerobic growth, but these strains grow as well as the wild type microaerobically.	complete CACAO 2747
involved_in	GO:0045454	cell redox homeostasis		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040309 MGI:MGI:1859815 PANTHER:PTN000073874 PomBase:SPCC576.03c SGD:S000002861 SGD:S000004490 UniProtKB:P9WQB7	P		Seeded From UniProt	complete
involved_in	GO:0042744	hydrogen peroxide catabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000189947 FB:FBgn0040308 FB:FBgn0040309 MGI:MGI:109486 PANTHER:PTN000073874 PomBase:SPCC576.03c UniProtKB:Q06830 UniProtKB:Q6ER94	P		Seeded From UniProt	complete
involved_in	GO:0033214	siderophore-dependent iron import into cell		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG11384 PANTHER:PTN000074131	P		Seeded From UniProt	complete
enables	GO:0008379	thioredoxin peroxidase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000189947 FB:FBgn0040308 FB:FBgn0040309 PANTHER:PTN000073874 PomBase:SPCC576.03c SGD:S000002861 SGD:S000004490 UniProtKB:P32119 UniProtKB:Q06830 UniProtKB:Q8I5Q6 UniProtKB:Q8IL80	F		Seeded From UniProt	complete
involved_in	GO:0006979	response to oxidative stress		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040308 FB:FBgn0040309 MGI:MGI:99523 PANTHER:PTN000073874 RGD:3838 RGD:620039 UniProtKB:P32119 UniProtKB:Q8I5Q6 UniProtKB:Q8IL80	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG11384 FB:FBgn0040308 FB:FBgn0040309 MGI:MGI:1859815 PANTHER:PTN000073874 RGD:3838 RGD:620039 SGD:S000004490 UniProtKB:Q8IL80	C		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0016209	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0051920	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008379	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0016209	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004601	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0051920	P		Seeded From UniProt	complete
involved_in	GO:0006979	response to oxidative stress	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017559	P		Seeded From UniProt	complete
enables	GO:0016209	antioxidant activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000866	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000866	F		Seeded From UniProt	complete
involved_in	GO:0045454	cell redox homeostasis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013766	P		Seeded From UniProt	complete
enables	GO:0051920	peroxiredoxin activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017559 InterPro:IPR019479	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000866 InterPro:IPR017559 InterPro:IPR019479	P		Seeded From UniProt	complete
enables	GO:0051920	peroxiredoxin activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.11.1.15	F		Seeded From UniProt	complete
enables	GO:0016209	antioxidant activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0049	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0004601	peroxidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0575	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
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References

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