GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

BACAN:Q81PQ3

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Bacillus anthracis. (1392)
Gene Name(s) sleB (ECO:0000313 with EMBL:AAP26584.1)
Protein Name(s) Hydrolase (ECO:0000313 with EMBL:AIF56912.1)

Spore cortex-lytic enzyme (ECO:0000313 with EMBL:AIK32043.1) Spore cortex-lytic enzyme prepeptide (ECO:0000313 with EMBL:AAP26584.1) Spore cortex-lytic enzyme, lytic transglycosylase SleB (ECO:0000313 with EMBL:AIK08801.1)

External Links
UniProt Q81PQ3
EMBL AE016879
AE017334
AE017225
CP008846
CP007660
CP007618
CP008752
CP007704
CP008853
CP008854
JNOD01000013
JMPV01000008
JMPU01000016
RefSeq NP_845098.1
YP_019388.1
YP_028821.1
PDB 4FET
PDBsum 4FET
STRING 198094.BA_2748
DNASU 1084998
EnsemblBacteria AAP26584
AAT31863
AAT54872
GeneID 1084998
2814463
2848393
KEGG ban:BA_2748
bar:GBAA_2748
bat:BAS2562
HOGENOM HOG000055262
KO K01449
OMA FYNGKID
OrthoDB EOG6XWV4B
BioCyc ANTHRA:SLEB-MONOMER
BANT260799:GJAJ-2626-MONOMER
BANT261594:GJ7F-2719-MONOMER
Proteomes UP000000427
UP000000594
UP000005639
GO GO:0003796
GO:0008152
GO:0009847
Gene3D 1.10.101.10
InterPro IPR011105
IPR002477
IPR014224
Pfam PF07486
PF01471
SUPFAM SSF47090
TIGRFAMs TIGR02869

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003796

lysozyme activity

PMID:20971910[1]

ECO:0000315

F

SleB functions to breaks down peptidoglycan (PG) by hydrolysis this is known as lysozyme activity. Table 1 compares the WT and mutant forms of the protein SleB. The WT form of the protein leads to 96% of the PG being solubilized whereas the mutant form only leads to 14% of the PG being solubilized.

complete
CACAO 4310

enables

GO:0003796

lysozyme activity

PMID:20971910[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030436

asexual sporulation

PMID:12721629[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P50739

P

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

PMID:12721629[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P50739

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014224

F

Seeded From UniProt

complete

involved_in

GO:0009847

spore germination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014224

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011105

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Heffron, JD et al. (2011) In vitro studies of peptidoglycan binding and hydrolysis by the Bacillus anthracis germination-specific lytic enzyme SleB. J. Bacteriol. 193 125-31 PubMed GONUTS page
  2. 2.0 2.1 Read, TD et al. (2003) The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature 423 81-6 PubMed GONUTS page