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ASFB7:P12

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Species (Taxon ID) African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)(ASFV). (10498)
Gene Name(s) No Information Provided.
Protein Name(s) Virus attachment protein p12

Protein p12

External Links
UniProt P32510
EMBL M84178
M84186
U18466
PIR A41998
RefSeq NP_042791.1
GeneID 1488862
Proteomes UP000000624
GO GO:0016021
GO:0019031
GO:0019012
GO:0055036
GO:0019062

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019012

virion

PMID:8350406[1]

ECO:0000314

C

As seen in Figure 1, immunoprecipitation of protein p12 of infected Vero cells and purified virions are compared, demonstrating that the function of p12 is to attach ASFV to a host cell receptor.

complete
CACAO 6347

GO:0019062

viral attachment to host cell

PMID:8350406[1]

ECO:0000314

P

As seen in Figure 6, when purified p12 is bound to the cell receptor, ASFV is unable to bind to the receptor. This is shown when the cell monolayers are washed with PBS and radiolabeled (radioactive I-125) ASFV is washed away, decreasing radioactivity.

complete
CACAO 6348

involved_in

GO:0019062

virion attachment to host cell

PMID:8350406[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0019012

virion

PMID:8350406[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0019031

viral envelope

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0261

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0055036

virion membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0275

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Angulo, A et al. (1993) Inhibition of African swine fever virus binding and infectivity by purified recombinant virus attachment protein p12. J. Virol. 67 5463-71 PubMed GONUTS page