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ARATH:TRXB1
Contents
| Species (Taxon ID) | Arabidopsis thaliana (Mouse-ear cress). (3702) | |
| Gene Name(s) | NTR1 (synonyms: NTRB) | |
| Protein Name(s) | Thioredoxin reductase 1
NADPH-dependent thioredoxin reductase 1 NTR1 NADPH-dependent thioredoxin reductase B AtNTRB | |
| External Links | ||
| UniProt | Q39243 | |
| EMBL | Z23109 AL117188 AL161587 CP002687 BT004322 | |
| PIR | S44027 T41743 | |
| RefSeq | NP_195271.2 | |
| UniGene | At.3705 At.69236 | |
| PDB | 1VDC | |
| PDBsum | 1VDC | |
| ProteinModelPortal | Q39243 | |
| SMR | Q39243 | |
| STRING | 3702.AT4G35460.1-P | |
| PaxDb | Q39243 | |
| PRIDE | Q39243 | |
| EnsemblPlants | AT4G35460.1 | |
| GeneID | 829698 | |
| KEGG | ath:AT4G35460 | |
| TAIR | AT4G35460 | |
| eggNOG | COG0492 | |
| HOGENOM | HOG000072912 | |
| InParanoid | Q39243 | |
| KO | K00384 | |
| OMA | MNGLETH | |
| PhylomeDB | Q39243 | |
| BioCyc | ARA:AT4G35460-MONOMER | |
| EvolutionaryTrace | Q39243 | |
| Proteomes | UP000006548 | |
| Genevestigator | Q39243 | |
| GO | GO:0009941 GO:0005829 GO:0005739 GO:0050660 GO:0004791 GO:0016049 GO:0045454 GO:0009846 GO:0019430 GO:0048316 GO:0042964 | |
| InterPro | IPR013027 IPR008255 IPR023753 IPR001327 IPR000103 IPR005982 | |
| Pfam | PF00070 PF07992 | |
| PRINTS | PR00368 PR00469 | |
| TIGRFAMs | TIGR01292 | |
| PROSITE | PS00573 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0051781 |
positive regulation of cell division |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
AGI_LocusCode:AT2G17420 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009941 |
chloroplast envelope |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004791 |
thioredoxin-disulfide reductase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004791 |
thioredoxin-disulfide reductase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004791 |
thioredoxin-disulfide reductase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
Missing: with/from | |||
|
enables |
GO:0004791 |
thioredoxin-disulfide reductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
| GO:0004791 |
thioredoxin-disulfide reductase activity |
ECO:0000314 |
F |
Figure 1 describes how the interaction between the oxidized Txnip and the reduced Trx1 form a disulfide bond, which results in the reduction of Trx/Txnip redoxisome. This down-regulates the expression of the redoxisome--Trx1 |
complete | |||||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019430 |
removal of superoxide radicals |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004791 |
thioredoxin-disulfide reductase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Reichheld, JP et al. (2007) Inactivation of thioredoxin reductases reveals a complex interplay between thioredoxin and glutathione pathways in Arabidopsis development. Plant Cell 19 1851-65 PubMed GONUTS page
- ↑ Froehlich, JE et al. () Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. J. Proteome Res. 2 413-25 PubMed GONUTS page
- ↑ 3.0 3.1 Reichheld, JP et al. (2005) AtNTRB is the major mitochondrial thioredoxin reductase in Arabidopsis thaliana. FEBS Lett. 579 337-42 PubMed GONUTS page
- ↑ 4.0 4.1 Jacquot, JP et al. (1994) Arabidopsis thaliana NAPHP thioredoxin reductase. cDNA characterization and expression of the recombinant protein in Escherichia coli. J. Mol. Biol. 235 1357-63 PubMed GONUTS page
- ↑ Laloi, C et al. (2001) Identification and characterization of a mitochondrial thioredoxin system in plants. Proc. Natl. Acad. Sci. U.S.A. 98 14144-9 PubMed GONUTS page
- ↑ Yoshihara, E et al. (2014) Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseases. Front Immunol 4 514 PubMed GONUTS page
