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ARATH:RHM2

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) RHM2 (ECO:0000303 with PMID:15134748[1]) (synonyms: MUM4 (ECO:0000303 with PMID:14701918[2]))
Protein Name(s) Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2 (ECO:0000305 with PMID:17190829[3])

NDP-rhamnose synthase Protein MUCILAGE-MODIFIED 4 Protein RHAMNOSE BIOSYNTHESIS 2 Rhamnose biosynthetic enzyme 2 AtRHM2 UDP-L-rhamnose synthase MUM4 UDP-glucose 4,6-dehydratase (ECO:0000303 with PMID:17190829[3]) UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose 4-keto-reductase (ECO:0000303 with PMID:17190829[3])

External Links
UniProt Q9LPG6
EMBL AJ565874
AY328518
AC018748
AC024260
CP002684
PIR B96575
RefSeq NP_564633.2
UniGene At.20215
ProteinModelPortal Q9LPG6
SMR Q9LPG6
BioGrid 27010
MINT MINT-8067929
PaxDb Q9LPG6
PRIDE Q9LPG6
EnsemblPlants AT1G53500.1
GeneID 841785
KEGG ath:AT1G53500
TAIR AT1G53500
eggNOG COG1088
HOGENOM HOG000167988
InParanoid Q9LPG6
KO K12450
OMA ESSIQFV
PhylomeDB Q9LPG6
BioCyc MetaCyc:AT1G53500-MONOMER
Proteomes UP000006548
ExpressionAtlas Q9LPG6
Genevestigator Q9LPG6
GO GO:0005829
GO:0050662
GO:0008831
GO:0008460
GO:0010489
GO:0010490
GO:0050377
GO:0010280
GO:0045226
GO:0010192
GO:0010214
GO:0010253
Gene3D 3.40.50.720
InterPro IPR005888
IPR001509
IPR016040
IPR029903
PANTHER PTHR10366:SF41
Pfam PF01370
PF04321
TIGRFAMs TIGR01181

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0050377

UDP-glucose 4,6-dehydratase activity

PMID:17190829[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0010280

UDP-L-rhamnose synthase activity

PMID:17190829[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0010280

UDP-L-rhamnose synthase activity

PMID:14701918[2]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0010253

UDP-rhamnose biosynthetic process

PMID:17190829[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010214

seed coat development

PMID:14671019[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010192

mucilage biosynthetic process

PMID:11706181[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21166475[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008460

dTDP-glucose 4,6-dehydratase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005888

F

Seeded From UniProt

complete

involved_in

GO:0009225

nucleotide-sugar metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005888

P

Seeded From UniProt

complete

enables

GO:0050377

UDP-glucose 4,6-dehydratase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.1.76

F

Seeded From UniProt

complete

enables

GO:0010490

UDP-4-keto-rhamnose-4-keto-reductase activity

PMID:17190829[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0010489

UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity

PMID:17190829[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0511

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0511

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Seifert, GJ (2004) Nucleotide sugar interconversions and cell wall biosynthesis: how to bring the inside to the outside. Curr. Opin. Plant Biol. 7 277-84 PubMed GONUTS page
  2. 2.0 2.1 Western, TL et al. (2004) MUCILAGE-MODIFIED4 encodes a putative pectin biosynthetic enzyme developmentally regulated by APETALA2, TRANSPARENT TESTA GLABRA1, and GLABRA2 in the Arabidopsis seed coat. Plant Physiol. 134 296-306 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Oka, T et al. (2007) Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion. J. Biol. Chem. 282 5389-403 PubMed GONUTS page
  4. Usadel, B et al. (2004) RHM2 is involved in mucilage pectin synthesis and is required for the development of the seed coat in Arabidopsis. Plant Physiol. 134 286-95 PubMed GONUTS page
  5. Western, TL et al. (2001) Isolation and characterization of mutants defective in seed coat mucilage secretory cell development in Arabidopsis. Plant Physiol. 127 998-1011 PubMed GONUTS page
  6. Ito, J et al. (2011) Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. J. Proteome Res. 10 1571-82 PubMed GONUTS page