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ARATH:NRT21

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) NRT2.1 (synonyms: ACH1, LIN1, NRT2)
Protein Name(s) High-affinity nitrate transporter 2.1

AtNRT2:1 Protein ACH1 Protein LATERAL ROOT INITIATION 1

External Links
UniProt O82811
EMBL Z97058
AF019748
AF093754
AC026875
CP002684
PIR T51836
RefSeq NP_172288.1
UniGene At.5407
ProteinModelPortal O82811
SMR O82811
BioGrid 22568
IntAct O82811
STRING 3702.AT1G08090.1-P
TCDB 2.A.1.8.12
PaxDb O82811
PRIDE O82811
EnsemblPlants AT1G08090.1
GeneID 837327
KEGG ath:AT1G08090
TAIR AT1G08090
eggNOG COG2223
HOGENOM HOG000196276
InParanoid O82811
KO K02575
OMA GSEWNEQ
PhylomeDB O82811
Proteomes UP000006548
Genevestigator O82811
GO GO:0016021
GO:0016020
GO:0005886
GO:0015112
GO:0048527
GO:0042128
GO:0015706
GO:0010167
InterPro IPR011701
IPR020846
Pfam PF07690
SUPFAM SSF103473

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0015706

nitrate transport

PMID:20561257[1]

ECO:0000315

P

Figure 1 shows that ATnar2.1 mutants do not growth on low nitrate in comparison to the wildtype. Additionally growth can be restored to a level that closely parallels WT growth rates by transformation with a myc-tagged AtNAR2.1).

Figure 2 shows that mutant lacking the ATNRT2.1 polypeptide exhibit poor growth on low nitrate (also see page 743).

complete
CACAO 2408

involved_in

GO:0015706

nitrate transport

PMID:20561257[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048527

lateral root development

PMID:16415211[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048527

lateral root development

PMID:16157886[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:16157886[3]

ECO:0000250

sequence similarity evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

involved_in

GO:0015706

nitrate transport

PMID:16415211[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015706

nitrate transport

PMID:11165253[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010167

response to nitrate

PMID:16415212[5]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:22227893[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0071249

cellular response to nitrate

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001160805
TAIR:locus:2159280

P

Seeded From UniProt

complete

involved_in

GO:0015706

nitrate transport

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001160805
TAIR:locus:2159280
TAIR:locus:2205190
TAIR:locus:2205195
TAIR:locus:2222652
UniProtKB:P0DKG9
UniProtKB:P0DKH0

P

Seeded From UniProt

complete

enables

GO:0015112

nitrate transmembrane transporter activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001160805
TAIR:locus:2159280
TAIR:locus:2222652

F

Seeded From UniProt

complete

part_of

GO:0009705

plant-type vacuole membrane

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001160805
TAIR:locus:2222652

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001160805
TAIR:locus:2010391
TAIR:locus:2075909
TAIR:locus:2159280
TAIR:locus:2205190

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011701

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011701

P

Seeded From UniProt

complete

enables

GO:0015112

nitrate transmembrane transporter activity

PMID:16157886[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0042128

nitrate assimilation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0534

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Yong, Z et al. (2010) Characterization of an intact two-component high-affinity nitrate transporter from Arabidopsis roots. Plant J. 63 739-48 PubMed GONUTS page
  2. 2.0 2.1 Remans, T et al. (2006) A central role for the nitrate transporter NRT2.1 in the integrated morphological and physiological responses of the root system to nitrogen limitation in Arabidopsis. Plant Physiol. 140 909-21 PubMed GONUTS page
  3. 3.0 3.1 3.2 Little, DY et al. (2005) The putative high-affinity nitrate transporter NRT2.1 represses lateral root initiation in response to nutritional cues. Proc. Natl. Acad. Sci. U.S.A. 102 13693-8 PubMed GONUTS page
  4. Filleur, S et al. (2001) An arabidopsis T-DNA mutant affected in Nrt2 genes is impaired in nitrate uptake. FEBS Lett. 489 220-4 PubMed GONUTS page
  5. Okamoto, M et al. (2006) High-affinity nitrate transport in roots of Arabidopsis depends on expression of the NAR2-like gene AtNRT3.1. Plant Physiol. 140 1036-46 PubMed GONUTS page
  6. Kiba, T et al. (2012) The Arabidopsis nitrate transporter NRT2.4 plays a double role in roots and shoots of nitrogen-starved plants. Plant Cell 24 245-58 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 7.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page