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ARATH:NIA1

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) NIA1
Protein Name(s) Nitrate reductase [NADH] 1

NR1

External Links
UniProt P11832
EMBL Z19050
AC012193
CP002684
AY090950
AF424624
BT000989
X13434
X13436
PIR E96807
S35228
RefSeq NP_177899.1
UniGene At.17771
ProteinModelPortal P11832
SMR P11832
BioGrid 29331
IntAct P11832
STRING 3702.AT1G77760.1-P
PaxDb P11832
PRIDE P11832
EnsemblPlants AT1G77760.1
GeneID 844112
KEGG ath:AT1G77760
TAIR AT1G77760
eggNOG COG0543
HOGENOM HOG000252609
InParanoid P11832
KO K10534
OMA QESAWIV
PhylomeDB P11832
BioCyc MetaCyc:AT1G77760-MONOMER
Proteomes UP000006548
ExpressionAtlas P11832
Genevestigator P11832
GO GO:0005829
GO:0009055
GO:0050660
GO:0020037
GO:0005506
GO:0030151
GO:0043546
GO:0009703
GO:0008940
GO:0042128
GO:0006809
GO:0009635
GO:0009416
Gene3D 2.60.40.650
3.10.120.10
3.90.420.10
InterPro IPR001199
IPR018506
IPR017927
IPR001709
IPR014756
IPR005066
IPR008335
IPR001834
IPR012137
IPR008333
IPR001433
IPR000572
IPR022407
IPR017938
Pfam PF00173
PF00970
PF03404
PF00175
PF00174
PIRSF PIRSF000233
PRINTS PR00406
PR00363
PR00407
PR00371
SUPFAM SSF55856
SSF56524
SSF63380
SSF81296
PROSITE PS00191
PS50255
PS51384
PS00559

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0008940

nitrate reductase activity

PMID:21772271[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0042128

nitrate assimilation

PMID:8510658[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009416

response to light stimulus

PMID:15908593[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008940

nitrate reductase activity

PMID:8510658[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006809

nitric oxide biosynthetic process

PMID:12446847[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0071949

FAD binding

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000452227
UniProtKB:P00387

F

Seeded From UniProt

complete

involved_in

GO:0042128

nitrate assimilation

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000452381
TAIR:locus:2029677
TAIR:locus:2203221

P

Seeded From UniProt

complete

enables

GO:0009703

nitrate reductase (NADH) activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000452381
TAIR:locus:2029677

F

Seeded From UniProt

complete

involved_in

GO:0006809

nitric oxide biosynthetic process

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000452381
TAIR:locus:2029677
TAIR:locus:2203221

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000452381
TAIR:locus:2029677

C

Seeded From UniProt

complete

involved_in

GO:0006809

nitric oxide biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012137

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR001834
InterPro:IPR005066
InterPro:IPR008335
InterPro:IPR017927

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018506

F

Seeded From UniProt

complete

enables

GO:0030151

molybdenum ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005066

F

Seeded From UniProt

complete

involved_in

GO:0042128

nitrate assimilation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000572
InterPro:IPR012137
InterPro:IPR036374

P

Seeded From UniProt

complete

enables

GO:0043546

molybdopterin cofactor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022407

F

Seeded From UniProt

complete

GO:0008940

nitrate reductase activity

PMID:21772271[1]

ECO:0000314

F

Fig. 4b shows how sumoylation increased NR activity in NIA1 and NIA2 in Arabidopsis.

complete
CACAO 2793

enables

GO:0050464

nitrate reductase (NADPH) activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012137

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001433
InterPro:IPR001709
InterPro:IPR001834
InterPro:IPR005066
InterPro:IPR008335
InterPro:IPR017927
InterPro:IPR022407

P

Seeded From UniProt

complete

enables

GO:0009703

nitrate reductase (NADH) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.7.1.1

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:15012211[6]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0009635

response to herbicide

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0359

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

involved_in

GO:0042128

nitrate assimilation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0534

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Park, BS et al. (2011) Arabidopsis nitrate reductase activity is stimulated by the E3 SUMO ligase AtSIZ1. Nat Commun 2 400 PubMed GONUTS page
  2. 2.0 2.1 Wilkinson, JQ & Crawford, NM (1993) Identification and characterization of a chlorate-resistant mutant of Arabidopsis thaliana with mutations in both nitrate reductase structural genes NIA1 and NIA2. Mol. Gen. Genet. 239 289-97 PubMed GONUTS page
  3. Cookson, SJ et al. (2005) Light-dark changes in cytosolic nitrate pools depend on nitrate reductase activity in Arabidopsis leaf cells. Plant Physiol. 138 1097-105 PubMed GONUTS page
  4. Desikan, R et al. (2002) A new role for an old enzyme: nitrate reductase-mediated nitric oxide generation is required for abscisic acid-induced stomatal closure in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A. 99 16314-8 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  6. Campbell, WH (1999) NITRATE REDUCTASE STRUCTURE, FUNCTION AND REGULATION: Bridging the Gap between Biochemistry and Physiology. Annu. Rev. Plant Physiol. Plant Mol. Biol. 50 277-303 PubMed GONUTS page