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ARATH:ICS1

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) ICS1
Protein Name(s) Isochorismate synthase 1, chloroplastic

AtIcs1 IcsI Enhanced disease susceptibility 16 Eds16 Isochorismate mutase 1 Salicylic acid induction deficient 2 Sid2 menF-like protein 1

External Links
UniProt Q9S7H8
EMBL AF078080
AY056055
AC008263
AC011765
CP002684
CP002684
AF367342
AY124864
PIR D96776
T51711
RefSeq NP_565090.1
NP_974143.1
UniGene At.22628
ProteinModelPortal Q9S7H8
SMR Q9S7H8
PaxDb Q9S7H8
PRIDE Q9S7H8
EnsemblPlants AT1G74710.1
GeneID 843810
KEGG ath:AT1G74710
TAIR AT1G74710
eggNOG COG1169
HOGENOM HOG000006336
InParanoid Q9S7H8
KO K02552
OMA DMEIERD
PhylomeDB Q9S7H8
BioCyc ARA:GQT-708-MONOMER
MetaCyc:AT1G74710-MONOMER
BRENDA 5.4.4.2
SABIO-RK Q9S7H8
UniPathway UPA00025
Proteomes UP000006548
ExpressionAtlas Q9S7H8
Genevestigator Q9S7H8
GO GO:0009507
GO:0009536
GO:0008909
GO:0006952
GO:0042742
GO:0050832
GO:0031348
GO:0042372
GO:0009617
GO:0009409
GO:0009697
GO:0010118
GO:0009627
Gene3D 3.60.120.10
InterPro IPR005801
IPR015890
IPR004561
PANTHER PTHR11236:SF3
Pfam PF00425
SUPFAM SSF56322
TIGRFAMs TIGR00543

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008909

isochorismate synthase activity

PMID:11734859[1]

ECO:0000247

UniProtKB:Q9M9V6


F

Fig. 2d indicates a clustal alignment of the Arabidpopsis ICS1 region with selected isochorismate synthases. Note the identical regions in black and the conserved regions in gray, as well as the critical regions shared for ICS activity (blue asterisk)

complete
CACAO 4245

enables

GO:0008909

isochorismate synthase activity

PMID:11734859[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:Q9M9V6

F

Seeded From UniProt

complete

involved_in

GO:0060866

leaf abscission

PMID:29253890[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050832

defense response to fungus

PMID:17513501[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

PMID:29253890[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

PMID:16959575[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042372

phylloquinone biosynthetic process

PMID:18451262[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042372

phylloquinone biosynthetic process

PMID:16617180[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031348

negative regulation of defense response

PMID:16732289[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010118

stomatal movement

PMID:16959575[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009627

systemic acquired resistance

PMID:17419843[8]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009617

response to bacterium

PMID:15842626[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009536

plastid

PMID:18451262[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009536

plastid

PMID:11734859[1]

ECO:0000250

sequence similarity evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

involved_in

GO:0009409

response to cold

PMID:23581962[10]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008909

isochorismate synthase activity

PMID:18451262[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0042372

phylloquinone biosynthetic process

PMID:21873635[11]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000881689
TAIR:locus:2019245
UniProtKB:Q9M9V6

P

Seeded From UniProt

complete

part_of

GO:0009536

plastid

PMID:21873635[11]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000881689
TAIR:locus:2019245
UniProtKB:Q9M9V6

C

Seeded From UniProt

complete

enables

GO:0008909

isochorismate synthase activity

PMID:21873635[11]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12362
PANTHER:PTN002933146
TAIR:locus:2019245
UniProtKB:Q9M9V6

F

Seeded From UniProt

complete

enables

GO:0008909

isochorismate synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004561

F

Seeded From UniProt

complete

involved_in

GO:0009058

biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004561
InterPro:IPR005801

P

Seeded From UniProt

complete

enables

GO:0008909

isochorismate synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.4.4.2

F

Seeded From UniProt

complete

involved_in

GO:0009697

salicylic acid biosynthetic process

PMID:15842626[9]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008909

isochorismate synthase activity

PMID:11734859[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0611

P

Seeded From UniProt

complete

part_of

GO:0009536

plastid

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0934

C

Seeded From UniProt

complete

part_of

GO:0009507

chloroplast

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0150
UniProtKB-SubCell:SL-0049

C

Seeded From UniProt

complete

involved_in

GO:0009697

salicylic acid biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00025

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Wildermuth, MC et al. (2001) Isochorismate synthase is required to synthesize salicylic acid for plant defence. Nature 414 562-5 PubMed GONUTS page
  2. 2.0 2.1 Patharkar, OR et al. (2017) Leaf shedding as an anti-bacterial defense in Arabidopsis cauline leaves. PLoS Genet. 13 e1007132 PubMed GONUTS page
  3. Adie, BA et al. (2007) ABA is an essential signal for plant resistance to pathogens affecting JA biosynthesis and the activation of defenses in Arabidopsis. Plant Cell 19 1665-81 PubMed GONUTS page
  4. 4.0 4.1 Melotto, M et al. (2006) Plant stomata function in innate immunity against bacterial invasion. Cell 126 969-80 PubMed GONUTS page
  5. 5.0 5.1 5.2 Garcion, C et al. (2008) Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of Arabidopsis. Plant Physiol. 147 1279-87 PubMed GONUTS page
  6. Gross, J et al. (2006) A plant locus essential for phylloquinone (vitamin K1) biosynthesis originated from a fusion of four eubacterial genes. J. Biol. Chem. 281 17189-96 PubMed GONUTS page
  7. Consonni, C et al. (2006) Conserved requirement for a plant host cell protein in powdery mildew pathogenesis. Nat. Genet. 38 716-20 PubMed GONUTS page
  8. Mishina, TE & Zeier, J (2007) Pathogen-associated molecular pattern recognition rather than development of tissue necrosis contributes to bacterial induction of systemic acquired resistance in Arabidopsis. Plant J. 50 500-13 PubMed GONUTS page
  9. 9.0 9.1 Prithiviraj, B et al. (2005) Staphylococcus aureus pathogenicity on Arabidopsis thaliana is mediated either by a direct effect of salicylic acid on the pathogen or by SA-dependent, NPR1-independent host responses. Plant J. 42 417-32 PubMed GONUTS page
  10. Kim, Y et al. (2013) Roles of CAMTA transcription factors and salicylic acid in configuring the low-temperature transcriptome and freezing tolerance of Arabidopsis. Plant J. 75 364-76 PubMed GONUTS page
  11. 11.0 11.1 11.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page