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ARATH:HAL3A
Contents
| Species (Taxon ID) | Arabidopsis thaliana (Mouse-ear cress). (3702) | |
| Gene Name(s) | HAL3A (synonyms: COAC1) | |
| Protein Name(s) | Phosphopantothenoylcysteine decarboxylase
PPCDC AtCoaC1 Halotolerance protein Hal3a AtHal3a | |
| External Links | ||
| UniProt | Q9SWE5 | |
| EMBL | AF166262 AB026641 CP002686 BT014781 BT015689 AK228559 | |
| RefSeq | NP_188430.1 | |
| UniGene | At.24652 | |
| PDB | 1E20 1MVL 1MVN | |
| PDBsum | 1E20 1MVL 1MVN | |
| ProteinModelPortal | Q9SWE5 | |
| SMR | Q9SWE5 | |
| BioGrid | 6660 | |
| PaxDb | Q9SWE5 | |
| PRIDE | Q9SWE5 | |
| DNASU | 821327 | |
| EnsemblPlants | AT3G18030.1 | |
| GeneID | 821327 | |
| KEGG | ath:AT3G18030 | |
| TAIR | AT3G18030 | |
| eggNOG | COG0452 | |
| HOGENOM | HOG000187629 | |
| KO | K01598 | |
| OMA | MEPKASC | |
| PhylomeDB | Q9SWE5 | |
| Reactome | REACT_248597 | |
| UniPathway | UPA00241 | |
| EvolutionaryTrace | Q9SWE5 | |
| Proteomes | UP000006548 | |
| Genevestigator | Q9SWE5 | |
| GO | GO:0005829 GO:0004633 GO:0015937 GO:0042538 GO:0040008 | |
| Gene3D | 3.40.50.1950 | |
| InterPro | IPR003382 | |
| Pfam | PF02441 | |
| SUPFAM | SSF52507 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0015937 |
coenzyme A biosynthetic process |
ECO:0000315 |
P |
Based on Fig. 5 and 6; Total fatty acid and acyl-CoA measurements of 5-d-old aaBb (null for HAL3A and heterozygous for HAL3B) seedlings in medium lacking Suc revealed stalled storage lipid catabolism and impaired CoA biosynthesis; in particular, acetyl-CoA levels were reduced by approximately 80%. Taken together, these results provide in vivo evidence for the function of HAL3A and HAL3B, and they point out the critical role of CoA biosynthesis during early postgerminative growth. |
complete | |||||
|
involved_in |
GO:0015937 |
coenzyme A biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042538 |
hyperosmotic salinity response |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042538 |
hyperosmotic salinity response |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004633 |
phosphopantothenoylcysteine decarboxylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004633 |
phosphopantothenoylcysteine decarboxylase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015937 |
coenzyme A biosynthetic process |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004633 |
phosphopantothenoylcysteine decarboxylase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016831 |
carboxy-lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0040008 |
regulation of growth |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015937 |
coenzyme A biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0173 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Rubio, S et al. (2006) An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment. Plant Physiol. 140 830-43 PubMed GONUTS page
- ↑ 2.0 2.1 Espinosa-Ruiz, A et al. (1999) Arabidopsis thaliana AtHAL3: a flavoprotein related to salt and osmotic tolerance and plant growth. Plant J. 20 529-39 PubMed GONUTS page
- ↑ Ito, J et al. (2011) Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. J. Proteome Res. 10 1571-82 PubMed GONUTS page
- ↑ Kupke, T et al. (2003) 4'-phosphopantetheine and coenzyme A biosynthesis in plants. J. Biol. Chem. 278 38229-37 PubMed GONUTS page
