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ARATH:FRDA
Contents
| Species (Taxon ID) | Arabidopsis thaliana (Mouse-ear cress). (3702) | |
| Gene Name(s) | FH | |
| Protein Name(s) | Frataxin, mitochondrial
Fxn | |
| External Links | ||
| UniProt | Q9ZR07 | |
| EMBL | AY649366 AC005275 AL161496 CP002687 BT014964 AK176448 AK176831 | |
| PIR | B85041 | |
| RefSeq | NP_192233.2 | |
| UniGene | At.50317 | |
| ProteinModelPortal | Q9ZR07 | |
| SMR | Q9ZR07 | |
| BioGrid | 13304 | |
| STRING | 3702.AT4G03240.1 | |
| PaxDb | Q9ZR07 | |
| PRIDE | Q9ZR07 | |
| EnsemblPlants | AT4G03240.1 | |
| GeneID | 828013 | |
| KEGG | ath:AT4G03240 | |
| TAIR | AT4G03240 | |
| eggNOG | COG1965 | |
| HOGENOM | HOG000190729 | |
| InParanoid | Q9ZR07 | |
| KO | K19054 | |
| OMA | ANATIHD | |
| PhylomeDB | Q9ZR07 | |
| BioCyc | ARA:AT4G03240-MONOMER | |
| Reactome | R-ATH-1268020 R-ATH-1362409 | |
| PRO | PR:Q9ZR07 | |
| Proteomes | UP000006548 | |
| GO | GO:0005739 GO:0008199 GO:0004322 GO:0009060 GO:0006879 GO:0006783 GO:0006811 GO:0016226 GO:0042542 GO:0006979 | |
| Gene3D | 3.30.920.10 | |
| InterPro | IPR017789 IPR002908 IPR020895 | |
| PANTHER | PTHR16821 | |
| Pfam | PF01491 | |
| SUPFAM | SSF55387 | |
| TIGRFAMs | TIGR03421 TIGR03422 | |
| PROSITE | PS01344 PS50810 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005739 |
mitochondrion |
ECO:0000314 |
C |
Figure 1 a,b&d: A shows mitotracker staining showing mitochondria, B shows GFP florescence of AtFH-GFP, D shows the overlay of these two images in which shows overlapping where there are yellow spots. These yellow spots show that there is Frataxin in the mitochondria. |
complete | |||||
| GO:0009507 |
chloroplast |
ECO:0000314 |
C |
Figure 1 b,c,&e B shows GFP florescence of AtFH-GFP, C shows chlorophyll autoflorescence, and E shows the overlay of these two images in which yellow spots indicate overlapping. These yellow spots show that frataxin is present in the chloroplasts. |
complete | |||||
|
involved_in |
GO:1903329 |
regulation of iron-sulfur cluster assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042542 |
response to hydrogen peroxide |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009507 |
chloroplast |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009060 |
aerobic respiration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000423706 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0034986 |
iron chaperone activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0030092 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0018283 |
iron incorporation into metallo-sulfur cluster |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000423706 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008199 |
ferric iron binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000423706 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008198 |
ferrous iron binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000423706 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007005 |
mitochondrion organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1096879 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1096879 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0030092 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004322 |
ferroxidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000423706 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004322 |
ferroxidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008199 |
ferric iron binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016226 |
iron-sulfur cluster assembly |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004322 |
ferroxidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055072 |
iron ion homeostasis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006783 |
heme biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Turowski, VR et al. (2015) Frataxin Is Localized to Both the Chloroplast and Mitochondrion and Is Involved in Chloroplast Fe-S Protein Function in Arabidopsis. PLoS ONE 10 e0141443 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Busi, MV et al. (2004) Functional and molecular characterization of the frataxin homolog from Arabidopsis thaliana. FEBS Lett. 576 141-4 PubMed GONUTS page
- ↑ Busi, MV et al. (2006) Deficiency of Arabidopsis thaliana frataxin alters activity of mitochondrial Fe-S proteins and induces oxidative stress. Plant J. 48 873-82 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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