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ARATH:AHM7

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) HMA5
Protein Name(s) Probable copper-transporting ATPase HMA5

Probable copper-transporting ATPase 3 Protein HEAVY METAL ATPASE 5

External Links
UniProt Q9SH30
EMBL AC008047
CP002684
PIR B96660
RefSeq NP_176533.1
UniGene At.36129
ProteinModelPortal Q9SH30
SMR Q9SH30
BioGrid 27871
IntAct Q9SH30
PaxDb Q9SH30
PRIDE Q9SH30
EnsemblPlants AT1G63440.1
GeneID 842650
KEGG ath:AT1G63440
TAIR AT1G63440
eggNOG COG2217
HOGENOM HOG000250397
InParanoid Q9SH30
KO K17686
OMA SEENHIW
PhylomeDB Q9SH30
BioCyc ARA:AT1G63440-MONOMER
ARA:MONOMER-14503
MetaCyc:MONOMER-14503
Reactome REACT_232357
Proteomes UP000006548
ExpressionAtlas Q9SH30
Genevestigator Q9SH30
GO GO:0016021
GO:0005524
GO:0019829
GO:0005507
GO:0006825
GO:0010273
GO:0046688
Gene3D 2.70.150.10
3.40.1110.10
3.40.50.1000
InterPro IPR023299
IPR018303
IPR008250
IPR023214
IPR017969
IPR006121
IPR006122
IPR027256
IPR001757
Pfam PF00122
PF00403
PF00702
PRINTS PR00119
SUPFAM SSF55008
SSF56784
TIGRFAMs TIGR01525
TIGR01494
TIGR00003
PROSITE PS00154
PS01047
PS50846

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0046688

response to copper ion

PMID:18701674[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010273

detoxification of copper ion

PMID:16367966[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0099132

ATP hydrolysis coupled cation transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0019829

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023299

F

Seeded From UniProt

complete

enables

GO:0005507

copper ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006122

F

Seeded From UniProt

complete

involved_in

GO:0006812

cation transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027256

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001757
InterPro:IPR027256

C

Seeded From UniProt

complete

enables

GO:0019829

cation-transporting ATPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027256

F

Seeded From UniProt

complete

involved_in

GO:0030001

metal ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006121
InterPro:IPR017969
InterPro:IPR036163

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006121
InterPro:IPR017969
InterPro:IPR036163

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0006825

copper ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0187

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kobayashi, Y et al. (2008) Amino acid polymorphisms in strictly conserved domains of a P-type ATPase HMA5 are involved in the mechanism of copper tolerance variation in Arabidopsis. Plant Physiol. 148 969-80 PubMed GONUTS page
  2. Andrés-Colás, N et al. (2006) The Arabidopsis heavy metal P-type ATPase HMA5 interacts with metallochaperones and functions in copper detoxification of roots. Plant J. 45 225-36 PubMed GONUTS page