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ARATH:ABAH2

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) CYP707A2
Protein Name(s) Abscisic acid 8'-hydroxylase 2

ABA 8'-hydroxylase 2 Cytochrome P450 707A2

External Links
UniProt O81077
EMBL AC005315
CP002685
CP002685
AK230466
PIR T02739
RefSeq NP_001189629.1
NP_180473.1
UniGene At.50108
ProteinModelPortal O81077
SMR O81077
STRING 3702.AT2G29090.1-P
PaxDb O81077
PRIDE O81077
EnsemblPlants AT2G29090.1
AT2G29090.2
GeneID 817457
KEGG ath:AT2G29090
GeneFarm 1252
TAIR AT2G29090
eggNOG COG2124
HOGENOM HOG000237614
KO K09843
OMA ERMIGPE
PhylomeDB O81077
BioCyc ARA:GQT-2623-MONOMER
MetaCyc:AT2G29090-MONOMER
Reactome REACT_233212
UniPathway UPA00093
Proteomes UP000006548
Genevestigator O81077
GO GO:0016021
GO:0010295
GO:0020037
GO:0005506
GO:0046345
GO:0009687
GO:0048838
GO:0010114
GO:0009639
Gene3D 1.10.630.10
InterPro IPR001128
IPR017972
IPR002401
Pfam PF00067
PRINTS PR00463
PR00385
SUPFAM SSF48264
PROSITE PS00086

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010295

(+)-abscisic acid 8'-hydroxylase activity

PMID:15064374[1]

ECO:0000270

F

They demonstrated that the transcript levels of all four CYP707A (abscisic acid 8'-hydroxylase) genes increased in response to ABA (Figs. 3 and ​and 9A) and under various stress conditions (Fig. 9). In other words, ABA activates its own inactivation to PA via transcriptional activation of CYP707A gene expression.

complete
CACAO 4797

involved_in

GO:0048838

release of seed from dormancy

PMID:15044947[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0010295

(+)-abscisic acid 8'-hydroxylase activity

PMID:15044947[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

NOT|enables

GO:0010295

(+)-abscisic acid 8'-hydroxylase activity

PMID:15064374[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0010114

response to red light

PMID:17449805[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009687

abscisic acid metabolic process

PMID:16543410[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009639

response to red or far red light

PMID:17010113[5]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001209376
TAIR:locus:2040929
TAIR:locus:2040939
TAIR:locus:2094058
UniProtKB:Q6V0L0
UniProtKB:Q9NR63

P

Seeded From UniProt

complete

involved_in

GO:0016125

sterol metabolic process

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001209376
UniProtKB:P9WPP9

P

Seeded From UniProt

complete

involved_in

GO:0009687

abscisic acid metabolic process

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000669512
TAIR:locus:2066138
UniProtKB:Q949P1

P

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000669383
TAIR:locus:2098802
TAIR:locus:2152292
UniProtKB:Q5CCK3
UniProtKB:Q8GSQ1

F

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR036396

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0503

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0046345

abscisic acid catabolic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00093

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Saito, S et al. (2004) Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acid. Plant Physiol. 134 1439-49 PubMed GONUTS page
  2. 2.0 2.1 Kushiro, T et al. (2004) The Arabidopsis cytochrome P450 CYP707A encodes ABA 8'-hydroxylases: key enzymes in ABA catabolism. EMBO J. 23 1647-56 PubMed GONUTS page
  3. Oh, E et al. (2007) PIL5, a phytochrome-interacting bHLH protein, regulates gibberellin responsiveness by binding directly to the GAI and RGA promoters in Arabidopsis seeds. Plant Cell 19 1192-208 PubMed GONUTS page
  4. Okamoto, M et al. (2006) CYP707A1 and CYP707A2, which encode abscisic acid 8'-hydroxylases, are indispensable for proper control of seed dormancy and germination in Arabidopsis. Plant Physiol. 141 97-107 PubMed GONUTS page
  5. Seo, M et al. (2006) Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism. Plant J. 48 354-66 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page