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ANESU:TXA2

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Species (Taxon ID) Anemonia sulcata (Mediterranean snakelocks sea anemone) (Anemoniaviridis). (6108)
Gene Name(s) No Information Provided.
Protein Name(s) Neurotoxin 2

Anemonia viridis toxin 2 Av2 As2 Toxin ATX-II Toxin II

External Links
UniProt P01528
PIR A91240
ProteinModelPortal P01528
SMR P01528
GO GO:0005576
GO:0042151
GO:0009966
Gene3D 2.20.20.10
InterPro IPR000693
IPR023355
Pfam PF00706
PIRSF PIRSF001905

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045759

negative regulation of action potential

PMID:1087023[1]

ECO:0000314

P

Fig. 1.B.

complete

GO:0045837

negative regulation of membrane potential

PMID:6197125[2]

ECO:0000314

P

Fig. 4. Depolarizing effect of toxin II on resting membrane potential

complete

GO:0014861

regulation of skeletal muscle contraction via membrane action potential

PMID:6197125[2]

ECO:0000314

P

Fig. 3

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000693

C

Seeded From UniProt

complete

involved_in

GO:0009966

regulation of signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000693

P

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

part_of

GO:0042151

nematocyst

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0166
UniProtKB-SubCell:SL-0177

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Romey, G et al. (1976) Sea anemone toxin:a tool to study molecular mechanisms of nerve conduction and excitation-secretion coupling. Proc. Natl. Acad. Sci. U.S.A. 73 4055-9 PubMed GONUTS page
  2. 2.0 2.1 Chang, CC et al. (1983) A study on the membrane depolarization of skeletal muscles caused by a scorpion toxin, sea anemone toxin II and crotamine and the interaction between toxins. Br. J. Pharmacol. 79 673-80 PubMed GONUTS page