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AGGAC:Q9S676

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Species (Taxon ID) Aggregatibacter actinomycetemcomitans (Actinobacillusactinomycetemcomitans) (Haemophilus actinomycetemcomitans). (714)
Gene Name(s) cdtB (ECO:0000313 with EMBL:AAD32072.1)
Protein Name(s) CdtB (ECO:0000313 with EMBL:AAQ72838.1)

Cytolethal distending toxin B (ECO:0000313 with EMBL:AAD32072.1)

External Links
UniProt Q9S676
EMBL AF102554
AY366473
ProteinModelPortal Q9S676
SMR Q9S676
GO GO:0009405
Gene3D 3.60.10.10
InterPro IPR003539
IPR005135
Pfam PF03372
PIRSF PIRSF018539
PRINTS PR01388
SUPFAM SSF56219

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008219

cell death

PMID:19995894[1]

ECO:0000315

P

according to figure 1, "expresion of cdtB is toxic to yeast cell" - decreased growth of cells was observed with expression of CdtB

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003539

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Matangkasombut, O et al. (2010) Cytolethal distending toxin from Aggregatibacter actinomycetemcomitans induces DNA damage, S/G2 cell cycle arrest, and caspase- independent death in a Saccharomyces cerevisiae model. Infect. Immun. 78 783-92 PubMed GONUTS page