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AGEAP:TOG4A

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Species (Taxon ID) Agelenopsis aperta (North American funnel-web spider) (Agelenopsisgertschi). (6908)
Gene Name(s) No Information Provided.
Protein Name(s) Omega-agatoxin-Aa4a

Omega-AGTX-Aa4a Omega-agatoxin IVA Omega-Aga-IVA Omega-agatoxin-4A

External Links
UniProt P30288
PIR S20256
PDB 1IVA
1OAV
1OAW
PDBsum 1IVA
1OAV
1OAW
ProteinModelPortal P30288
SMR P30288
TCDB 8.B.6.1.1
ArachnoServer AS000182
EvolutionaryTrace P30288
GO GO:0072556
GO:0019871
GO:0009405
Gene3D 4.10.40.10
InterPro IPR008017
IPR004169
Pfam PF02819

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019855

calcium channel inhibitor activity

PMID:9120560[1]

ECO:0000314

F

Fig. 6

complete
CACAO 4356

GO:0019855

calcium channel inhibitor activity

PMID:11055992[2]

ECO:0000314

F

Fig. 2

complete
CACAO 4357

GO:0019855

calcium channel inhibitor activity

PMID:9129813[3]

ECO:0000314

F

Fig. 1

complete
CACAO 4358

enables

GO:0019855

calcium channel inhibitor activity

PMID:9129813[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004169

C

Seeded From UniProt

complete

enables

GO:0008200

ion channel inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004169

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004169

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

part_of

GO:0072556

other organism presynaptic membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0638

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wicher, D & Penzlin, H (1997) Ca2+ currents in central insect neurons: electrophysiological and pharmacological properties. J. Neurophysiol. 77 186-99 PubMed GONUTS page
  2. Winterfield, JR & Swartz, KJ (2000) A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels. J. Gen. Physiol. 116 637-44 PubMed GONUTS page
  3. 3.0 3.1 McDonough, SI et al. (1997) Alteration of P-type calcium channel gating by the spider toxin omega-Aga-IVA. Biophys. J. 72 2117-28 PubMed GONUTS page