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ADE05:DNB2
Contents
| Species (Taxon ID) | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5). (28285) | |
| Gene Name(s) | DBP | |
| Protein Name(s) | Early E2A DNA-binding protein | |
| External Links | ||
| UniProt | P03265 | |
| EMBL | M73260 X02997 | |
| PIR | A03833 | |
| RefSeq | AP_000213.1 | |
| PDB | 1ADU 1ADV 1ANV 2WAZ 2WB0 | |
| PDBsum | 1ADU 1ADV 1ANV 2WAZ 2WB0 | |
| DisProt | DP00003 | |
| ProteinModelPortal | P03265 | |
| SMR | P03265 | |
| IntAct | P03265 | |
| MINT | MINT-216016 | |
| EvolutionaryTrace | P03265 | |
| Proteomes | UP000004992 | |
| GO | GO:0042025 GO:0019028 GO:0003677 GO:0008270 GO:0006260 GO:0006351 GO:0016032 | |
| Gene3D | 1.10.269.10 3.90.148.10 | |
| InterPro | IPR005376 IPR003176 | |
| Pfam | PF02236 PF03728 | |
| SUPFAM | SSF47724 SSF57917 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0019028 |
viral capsid |
ECO:0000314 |
C |
The results in Figure 5 indicate that DBP is located at a single site on the AdV virions. |
complete | |||||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045740 |
positive regulation of DNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039693 |
viral DNA genome replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039687 |
viral DNA strand displacement replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039693 |
viral DNA genome replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032508 |
DNA duplex unwinding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019028 |
viral capsid |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003176 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006351 |
transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032508 |
DNA duplex unwinding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045740 |
positive regulation of DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039687 |
viral DNA strand displacement replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0019028 |
viral capsid |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039693 |
viral DNA genome replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006351 |
transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523870 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039693 |
viral DNA genome replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ahi, YS et al. (2013) Adenoviral E2 IVa2 protein interacts with L4 33K protein and E2 DNA-binding protein. J. Gen. Virol. 94 1325-34 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Tucker, PA et al. (1994) Crystal structure of the adenovirus DNA binding protein reveals a hook-on model for cooperative DNA binding. EMBO J. 13 2994-3002 PubMed GONUTS page
- ↑ Morin, N et al. (1989) Nuclear localization of the adenovirus DNA-binding protein: requirement for two signals and complementation during viral infection. Mol. Cell. Biol. 9 4372-80 PubMed GONUTS page
- ↑ van Breukelen, B et al. (2003) Adenovirus type 5 DNA binding protein stimulates binding of DNA polymerase to the replication origin. J. Virol. 77 915-22 PubMed GONUTS page
- ↑ 5.0 5.1 Friefeld, BR et al. (1983) Effects of the adenovirus H5ts125 and H5ts107 DNA binding proteins on DNA replication in vitro. Virology 124 380-9 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Dekker, J et al. (1997) Multimerization of the adenovirus DNA-binding protein is the driving force for ATP-independent DNA unwinding during strand displacement synthesis. EMBO J. 16 1455-63 PubMed GONUTS page
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