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9VIRU:Q9FZR9

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Species (Taxon ID) Mycobacterium phage Ms6. (65388)
Gene Name(s) lysB (ECO:0000313 with EMBL:AAG48319.1)
Protein Name(s) Gp3 (ECO:0000313 with EMBL:AAG48319.1)
External Links
UniProt Q9FZR9
EMBL AF319619
ProteinModelPortal Q9FZR9
SMR Q9FZR9
Gene3D 3.40.50.1820
InterPro IPR029058
SUPFAM SSF53474

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016298

lipase activity

PMID:18451045[1]

ECO:0000314

F

The protein Q9FZR9 is involved in lipolytic activity as shown by figure 3. It was hypothesized to have that activity based on this motif. Gly-Tyr-Ser-Gln-Gly. The enzymatic activity done invitro matches this hypothesis. The paper is investigating additional proteins to help with cell lysis using the specific bacteriophage MS6 a phage that infects Mycobacterium smegmatis. They specifically look at the product of gene LysB which is the protein in question. Figure 3 demonstrates the lipolytic activity by using the product of LysB to produce a zone of clearance in plates coated with triglycerides such as triolein.

complete
CACAO 13198

Notes

References

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  1. Gil, F et al. (2008) The lytic cassette of mycobacteriophage Ms6 encodes an enzyme with lipolytic activity. Microbiology (Reading, Engl.) 154 1364-71 PubMed GONUTS page