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9STAP:A0A1F1MBJ8

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Species (Taxon ID) Staphylococcus sp. HMSC068D05. (1739420)
Gene Name(s) No Information Provided.
Protein Name(s) Heme uptake protein IsdC (ECO:0000313 with EMBL:OFS37376.1)
External Links
UniProt A0A1F1MBJ8
EMBL LWQG01000098
RefSeq WP_002460922.1
GeneID 29733188
BioCyc GCF_001813495-HMP:HMPREF2916_RS09435-MONOMER
Proteomes UP000186325
GO GO:0005576
GO:0016021
GO:0009274
GO:0030492
GO:0015886
CDD cd06920
InterPro IPR019909
IPR006635
IPR037250
IPR017505
Pfam PF05031
SMART SM00725
SUPFAM SSF158911
TIGRFAMs TIGR03656
TIGR03068
PROSITE PS50978

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:1900233

positive regulation of single-species biofilm formation on inanimate substrate

PMID:24686057[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Figure 4 first demonstrates how one or more proteins expressed by the isd locus are involved in biofilm formation in iron deficient environments, due to the ability of the mutant with the isd locus deleted to produce the same amount of biofilm as the wild-type. Furthermore in Figure 4, the isd mutant that lacked the entire isd locus bore an isdc gene engineered to express IsdC protein expression. Similar levels of biofilm formed in this mutant and the wild type. Therefore, IsdC is sufficient in promoting biofilm formation in low-iron environments all alone.

complete
CACAO 10078

part_of

GO:0009274

peptidoglycan-based cell wall

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019909

C

Seeded From UniProt

complete

involved_in

GO:0015886

heme transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019909

P

Seeded From UniProt

complete

enables

GO:0030492

hemoglobin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019909

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0041

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Missineo, A et al. (2014) IsdC from Staphylococcus lugdunensis induces biofilm formation under low-iron growth conditions. Infect. Immun. 82 2448-59 PubMed GONUTS page