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9RHAB:S5TDC0

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Species (Taxon ID) Vesicular stomatitis virus. (11276)
Gene Name(s) M (ECO:0000313 with EMBL:AGS42187.1)
Protein Name(s) Matrix protein (ECO:0000313 with EMBL:AGS42187.1)
External Links
UniProt S5TDC0
EMBL KC905171
KM012169
GO GO:0019031
GO:0005198
Gene3D 3.10.460.10
InterPro IPR009397
Pfam PF06326
SUPFAM SSF75404

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0039657

suppression by virus of host gene expression

PMID:12663771[1]

ECO:0000315

P

Fig 1D: cells were transfected with SV40-promoter-luciferase-reporter plasmid and wildtype or mutant M mRNA - wildtype inhibited luciferase expression, mutants didn't

Fig. 1C: expression of HR wildtype strain and mutants TP2 and TP3 were similar, meaning that decreased luciferase expression resulted from M protein mutations, not decreased M expression

complete
CACAO 9986

GO:0039501

suppression by virus of host type I interferon production

PMID:12663771[1]

ECO:0000315

P

Fig. 2: cells were transfected with IFN-beta-promoter-luciferase-reporter plasmid and wildtype or mutant M mRNA - wildtype inhibited luciferase expression, mutants didn't

complete
CACAO 9989

GO:0039653

suppression by virus of host transcription

PMID:12663771[1]

ECO:0000315

P

Fig. 6: cells were infected with wildtype or mutant viruses, wildtype inhibited RNA synthesis more than mutant

complete
CACAO 10010

GO:0039604

suppression by virus of host translation

PMID:12663771[1]

ECO:0000315

P

Fig. 7B: cells were infected with wildtype or mutant viruses, wildtype inhibited host cell protein synthesis more than mutant

complete
CACAO 10022

involved_in

GO:0039604

suppression by virus of host translation

PMID:12663771[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0039653

suppression by virus of host transcription

PMID:12663771[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0039501

suppression by virus of host type I interferon production

PMID:12663771[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009397
InterPro:IPR036711

F

Seeded From UniProt

complete

part_of

GO:0019031

viral envelope

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009397
InterPro:IPR036711

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Ahmed, M et al. (2003) Ability of the matrix protein of vesicular stomatitis virus to suppress beta interferon gene expression is genetically correlated with the inhibition of host RNA and protein synthesis. J. Virol. 77 4646-57 PubMed GONUTS page