GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
9CAUD:S5Y020
Contents
| Species (Taxon ID) | Bacillus phage Troll. (1382932) | |
| Gene Name(s) | 122 (ECO:0000313 with EMBL:AGT13404.1) | |
| Protein Name(s) | DUTP nucleotidohydrolase (ECO:0000313 with EMBL:AGT13404.1) | |
| External Links | ||
| UniProt | S5Y020 | |
| EMBL | KF208639 | |
| RefSeq | YP_008430906.1 | |
| GeneID | 16575378 | |
| GO | GO:0016787 GO:0046080 | |
| Gene3D | 2.70.40.10 | |
| InterPro | IPR029054 IPR008180 | |
| Pfam | PF00692 | |
| SUPFAM | SSF51283 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
incorrect (CACAO) |
GO:0046080 |
regulation of dUTP diphosphatase activity |
ECO:0000315 |
P |
The function of this gene in the T5 phage can be concluded from a mutant phenotype. Figure 4 in the referenced paper shows that the dut mutant T5 phage made was not able to induce dUTPase activity. This gives us evidence to conclude that the function of that gene is a dUTPase. IMP can also be assigned to this phage with evidence from an experimental paper that states the function of a dUTPase. |
complete | ||||
|
incorrect (CACAO) |
GO:0004170 |
dUTP diphosphatase activity |
ECO:0000247 |
|
F |
BlastP showed that the Troll gene is a homolog to a gene from another bacteriphage, Bacillus phage VB_BCEMBc431v3. The alignment gave an e-value of 1e-122, 93%query cover and 60% identity. Evidence for the function of the Bacillus phage gene is given through experimental evidence done on the phage, T5. The Troll gene also aligned with other dUTP diphosphatase proteins. This is evidence to conclude that the two genes are homologous. The function of this gene is in the reaction that converts dUTP to dUMP. |
complete | |||
|
enables |
GO:0004170 |
dUTP diphosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046080 |
dUTP metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Warner, HR et al. (1979) The properties of a bacteriophage T5 mutant unable to induce deoxyuridine 5'-triphosphate nucleotidohydrolase. Synthesis of uracil-containing T5 deoxyribonucleic acid. J. Biol. Chem. 254 7534-9 PubMed GONUTS page
