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9CAUD:Q7Y3F1

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Species (Taxon ID) Streptococcus phage C1. (230871)
Gene Name(s) orf11 (ECO:0000313 with EMBL:AAP42310.2)
Protein Name(s) PlyCA (ECO:0000313 with EMBL:AAP42310.2)
External Links
UniProt Q7Y3F1
EMBL AY212251
RefSeq NP_852017.2
PDB 4F88
PDBsum 4F88
SMR Q7Y3F1
DIP DIP-60064N
GeneID 1489936
KEGG vg:1489936
Proteomes UP000001773
InterPro IPR007921
Pfam PF05257
PROSITE PS50911

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003796

lysozyme activity

PMID:16818874[1]

ECO:0000315

F

FIGURE 6 shows that PlyCA contains a functional Cysteine, Histidine-Dependent Amidohydrolase Peptidase (CHAP) Domain confirming it to have amidase activity, because it is able to cleave the amide bond between N-acetyl muramic acid and L-alanine in the streptococcal peptidoglycan (Fischetti et al., 1972).

complete
CACAO 12766

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Nelson, D et al. (2006) PlyC: a multimeric bacteriophage lysin. Proc. Natl. Acad. Sci. U.S.A. 103 10765-70 PubMed GONUTS page