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9CAUD:A0A0K2CZY5
Contents
Species (Taxon ID) | Bacillus phage TsarBomba. (1690456) | |
Gene Name(s) | No Information Provided. | |
Protein Name(s) | Tail assembly chaperone (ECO:0000313 with EMBL:ALA13033.1) | |
External Links | ||
UniProt | A0A0K2CZY5 | |
EMBL | KT224359 | |
RefSeq | YP_009206906.1 | |
GeneID | 26633232 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0051131 |
chaperone-mediated protein complex assembly |
ECO:0000315 |
P |
"The requirement for co-expression of gpG and gpGT with gpH and the demonstration of a physical interaction between gpG and gpH argue that the nascent gpH polypeptide might require the binding of gpG and gpGT to fold correctly. This is consistent with the observation that gpG is expressed in a large amount similar to the level of the major tail protein gpV. Since gpG interacts with more than one part of gpH, the amount of gpG expressed is probably enough to coat the entire gpH. The large amount of gpG might ensure that gpH is properly chaperoned over its entire length. Since gpGT also uses its G part to interact with gpH, it is likely that some part of gpH is also bound with gpGT molecules. The observation that tail assembly can be disrupted by altering the ratio of gpG and gpGT production argues that the amount of gpGT incorporated is probably determined by the ratio of gpG versus gpGT, rather than by some sort of mechanism that assembles the “correct” ratio of gpGT to gpG regardless of the ratio in the unassembled pool. It also argues that having the correct ratio of gpGT to gpG in complex with gpH is important for successful assembly." |
complete | |||||
NOT |
GO:0051131 |
chaperone-mediated protein complex assembly |
ECO:0000250 |
UniProtKB:O64292 UniProtKB:P03734
|
P |
The order of tail genes is highly conserved. The major tail protein gene is always upstream of the tape measure protein gene |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Xu, J et al. (2014) Chaperone-protein interactions that mediate assembly of the bacteriophage lambda tail to the correct length. J. Mol. Biol. 426 1004-18 PubMed GONUTS page
- ↑ Xu, J et al. (2004) Conserved translational frameshift in dsDNA bacteriophage tail assembly genes. Mol. Cell 16 11-21 PubMed GONUTS page