HUMAN:PP1A

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	PPP1CA (synonyms: PPP1A)
Protein Name(s)	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP-1A
External Links
UniProt	P62136
EMBL	X70848 S57501 M63960 AK313586 BT006629 AP003419 BC001888 BC004482 BC008010 J04759
CCDS	CCDS31618.1 CCDS8160.1 CCDS8161.1
RefSeq	NP_001008709.1 NP_002699.1 NP_996756.1
UniGene	Hs.183994
PDB	3E7A 3E7B 3EGG 3EGH 3HVQ 3N5U 3V4Y 4G9J 4MOV 4MOY 4MP0
PDBsum	3E7A 3E7B 3EGG 3EGH 3HVQ 3N5U 3V4Y 4G9J 4MOV 4MOY 4MP0
ProteinModelPortal	P62136
SMR	P62136
BioGrid	111493
DIP	DIP-221N DIP-38195N
IntAct	P62136
MINT	MINT-5001223
STRING	9606.ENSP00000326031
BindingDB	P62136
ChEMBL	CHEMBL2164
DEPOD	P62136
PhosphoSite	P62136
DMDM	49065811
OGP	P08129
MaxQB	P62136
PaxDb	P62136
PRIDE	P62136
DNASU	5499
Ensembl	ENST00000312989 ENST00000358239 ENST00000376745
GeneID	5499
KEGG	hsa:5499
UCSC	uc001oku.1 uc001okw.1
CTD	5499
GeneCards	GC11M067165
HGNC	HGNC:9281
HPA	CAB004545
MIM	176875
neXtProt	NX_P62136
PharmGKB	PA33609
eggNOG	COG0639
GeneTree	ENSGT00530000062911
HOGENOM	HOG000172697
HOVERGEN	HBG000216
InParanoid	P62136
KO	K06269
OMA	GLETICL
OrthoDB	EOG7TJ3K3
PhylomeDB	P62136
TreeFam	TF354243
Reactome	REACT_120727 REACT_15334 REACT_494
SignaLink	P62136
ChiTaRS	PPP1CA
EvolutionaryTrace	P62136
GeneWiki	PPP1CA
GenomeRNAi	5499
NextBio	21272
PRO	PR:P62136
Proteomes	UP000005640
Bgee	P62136
CleanEx	HS_PPP1CA
ExpressionAtlas	P62136
Genevestigator	P62136
GO	GO:0005737 GO:0005829 GO:0043197 GO:0070062 GO:0042587 GO:0070688 GO:0005730 GO:0005634 GO:0043204 GO:0000164 GO:0072357 GO:0046872 GO:0016791 GO:0004722 GO:0043021 GO:0048754 GO:0007049 GO:0051301 GO:0032922 GO:0043153 GO:0005977 GO:0030324 GO:0030512 GO:2001241 GO:0006470 GO:0042752 GO:0005979 GO:0005981 GO:0044281 GO:0007179 GO:0019433
Gene3D	3.60.21.10
InterPro	IPR004843 IPR029052 IPR006186
Pfam	PF00149
PRINTS	PR00114
SMART	SM00156
SUPFAM	SSF56300
PROSITE	PS00125

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0016311	dephosphorylation	PMID:22311981^[1]	ECO:0000314			P		Figure 8	complete CACAO 3738
	GO:0006470	protein dephosphorylation	PMID:22311981^[1]	ECO:0000315			P		Figure 5: Knockdown of PP1 and PP2A isoforms in ERM dephosphorylation.	complete CACAO 5317
part_of	GO:0005913	cell-cell adherens junction	PMID:25468996^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
colocalizes_with	GO:0000784	nuclear chromosome, telomeric region	PMID:24270157^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1904886	beta-catenin destruction complex disassembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62139	P		Seeded From UniProt	complete
involved_in	GO:0060828	regulation of canonical Wnt signaling pathway	PMID:17318175^[4]	ECO:0000305	curator inference used in manual assertion	GO:0005515	P		Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62139	F	has_direct_input:(UniProtKB:O15169) part_of:(GO:1904886) part_of:(GO:0032091)	Seeded From UniProt	complete
involved_in	GO:0032091	negative regulation of protein binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62139	P	has_regulation_target:(UniProtKB:O15169) has_regulation_target:(UniProtKB:P49841) part_of:(GO:1904886)	Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62139	P	has_direct_input:(UniProtKB:O15169)	Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	PMID:22311981^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0098641	cadherin binding involved in cell-cell adhesion	PMID:25468996^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62139	P		Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	PMID:22311981^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:20458337^[5]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000639)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21630459^[6]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
involved_in	GO:0010288	response to lead ion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62138	P	occurs_in:(UBERON:0001885) causally_upstream_of:(GO:0007416) causally_upstream_of:(GO:0007611)	Seeded From UniProt	complete
part_of	GO:0072357	PTW/PP1 phosphatase complex	PMID:20516061^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0043153	entrainment of circadian clock by photoperiod	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62137	P		Seeded From UniProt	complete
involved_in	GO:0042752	regulation of circadian rhythm	PMID:21712997^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032922	circadian regulation of gene expression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62137	P		Seeded From UniProt	complete
enables	GO:0016791	phosphatase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62137	F		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62137	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:11739654^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11739654^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0043153	entrainment of circadian clock by photoperiod	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103016 MGI:MGI:104872 PANTHER:PTN002617081	P		Seeded From UniProt	complete
involved_in	GO:0042752	regulation of circadian rhythm	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103016 MGI:MGI:104872 PANTHER:PTN002617081 UniProtKB:P36873 UniProtKB:P62136	P		Seeded From UniProt	complete
enables	GO:0008157	protein phosphatase 1 binding	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002617081 RGD:3375 RGD:3377	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003140 MGI:MGI:103016 MGI:MGI:104871 MGI:MGI:104872 PANTHER:PTN000185232 PomBase:SPAC57A7.08 PomBase:SPBC776.02c PomBase:SPCC31H12.05c RGD:3375 RGD:3376 RGD:3377 SGD:S000000935 TAIR:locus:2024507 UniProtKB:P36873 UniProtKB:P62136 UniProtKB:P62140 UniProtKB:Q57YU1 UniProtKB:Q583K6 WB:WBGene00001748 WB:WBGene00020187 WB:WBGene00021113	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003140 FB:FBgn0025573 MGI:MGI:103016 PANTHER:PTN000185231 PomBase:SPBC776.02c PomBase:SPCC31H12.05c RGD:3375 SGD:S000000935 SGD:S000004478 TAIR:locus:2024507 TAIR:locus:2063942 TAIR:locus:2825042 UniProtKB:P20654 UniProtKB:Q583K6 UniProtKB:Q585J4 UniProtKB:Q59N42 WB:WBGene00001748 WB:WBGene00020187 WB:WBGene00021113	C		Seeded From UniProt	complete
enables	GO:0004722	protein serine/threonine phosphatase activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000711 FB:FBgn0003132 FB:FBgn0003140 FB:FBgn0004103 MGI:MGI:103016 MGI:MGI:104871 MGI:MGI:104872 PANTHER:PTN000185232 PomBase:SPAC57A7.08 PomBase:SPBC776.02c SGD:S000000935 SGD:S000004478 TAIR:locus:2024507 TAIR:locus:2043122 TAIR:locus:2063942 TAIR:locus:2078087 TAIR:locus:2102762 TAIR:locus:2128258 TAIR:locus:2168484 TAIR:locus:2180330 TAIR:locus:2825042 UniProtKB:P36873 UniProtKB:P62207 UniProtKB:Q57YU1 UniProtKB:Q59U06 WB:WBGene00001748	F		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	PMID:22801782^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0098609	cell-cell adhesion	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0098641	P		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
part_of	GO:0098794	postsynapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	F		Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
enables	GO:0043021	ribonucleoprotein complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	F		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
part_of	GO:0042587	glycogen granule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
involved_in	GO:0010288	response to lead ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	P		Seeded From UniProt	complete
enables	GO:0008157	protein phosphatase 1 binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	F		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	P		Seeded From UniProt	complete
involved_in	GO:0005981	regulation of glycogen catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	P		Seeded From UniProt	complete
involved_in	GO:0005979	regulation of glycogen biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	F		Seeded From UniProt	complete
part_of	GO:0000164	protein phosphatase type 1 complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62138 ensembl:ENSRNOP00000025282	C		Seeded From UniProt	complete
involved_in	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	P		Seeded From UniProt	complete
involved_in	GO:0048754	branching morphogenesis of an epithelial tube	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	P		Seeded From UniProt	complete
involved_in	GO:0043153	entrainment of circadian clock by photoperiod	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	P		Seeded From UniProt	complete
involved_in	GO:0042752	regulation of circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	P		Seeded From UniProt	complete
involved_in	GO:0032922	circadian regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	P		Seeded From UniProt	complete
involved_in	GO:0030324	lung development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	P		Seeded From UniProt	complete
enables	GO:0016791	phosphatase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	F		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	C		Seeded From UniProt	complete
enables	GO:0004722	protein serine/threonine phosphatase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	F		Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62137 ensembl:ENSMUSP00000039109	F		Seeded From UniProt	complete
part_of	GO:0000164	protein phosphatase type 1 complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037979	C		Seeded From UniProt	complete
enables	GO:0004722	protein serine/threonine phosphatase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037979	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004843 InterPro:IPR006186	F		Seeded From UniProt	complete
part_of	GO:0072357	PTW/PP1 phosphatase complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037979	C		Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.3.16	F		Seeded From UniProt	complete
involved_in	GO:0035970	peptidyl-threonine dephosphorylation	PMID:16262633^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070262	peptidyl-serine dephosphorylation	PMID:16262633^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004722	protein serine/threonine phosphatase activity	PMID:16262633^[12] PMID:8392016^[13] PMID:10640627^[14]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	has_direct_input:(UniProtKB:P10636)	Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	PMID:8392016^[13]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-180038	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0132	P		Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P		Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0904	F		Seeded From UniProt	complete
involved_in	GO:0005975	carbohydrate metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0119	P		Seeded From UniProt	complete
involved_in	GO:0005977	glycogen metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0321	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0190	C		Seeded From UniProt	complete
part_of	GO:0005730	nucleolus	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0188	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Canals, D et al. (2012) Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase. J. Biol. Chem. 287 10145-55 PubMed GONUTS page
↑ ^2.0 ^2.1 Guo, Z et al. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Sci Signal 7 rs7 PubMed GONUTS page
↑ Grolimund, L et al. (2013) A quantitative telomeric chromatin isolation protocol identifies different telomeric states. Nat Commun 4 2848 PubMed GONUTS page
↑ Luo, W et al. (2007) Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J. 26 1511-21 PubMed GONUTS page
↑ Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page
↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
↑ Lee, JH et al. (2010) Identification and characterization of a novel human PP1 phosphatase complex. J. Biol. Chem. 285 24466-76 PubMed GONUTS page
↑ Schmutz, I et al. (2011) Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock. PLoS ONE 6 e21325 PubMed GONUTS page
↑ ^9.0 ^9.1 Trinkle-Mulcahy, L et al. (2001) Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells. J. Cell. Sci. 114 4219-28 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 ^10.4 ^10.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Wurzenberger, C et al. (2012) Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J. Cell Biol. 198 173-83 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 Liu, F et al. (2005) Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur. J. Neurosci. 22 1942-50 PubMed GONUTS page
↑ ^13.0 ^13.1 Song, Q et al. (1993) Cloning and characterization of a human protein phosphatase 1-encoding cDNA. Gene 129 291-5 PubMed GONUTS page
↑ Gong, CX et al. (2000) Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain. Brain Res. 853 299-309 PubMed GONUTS page

[PMID:22311981-1] 1.0 ^1.1 ^1.2 ^1.3 Canals, D et al. (2012) Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase. J. Biol. Chem. 287 10145-55 PubMed GONUTS page

[PMID:25468996-2] 2.0 ^2.1 Guo, Z et al. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Sci Signal 7 rs7 PubMed GONUTS page

[PMID:24270157-3] Grolimund, L et al. (2013) A quantitative telomeric chromatin isolation protocol identifies different telomeric states. Nat Commun 4 2848 PubMed GONUTS page

[PMID:17318175-4] Luo, W et al. (2007) Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J. 26 1511-21 PubMed GONUTS page

[PMID:20458337-5] Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page

[PMID:21630459-6] Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page

[PMID:20516061-7] Lee, JH et al. (2010) Identification and characterization of a novel human PP1 phosphatase complex. J. Biol. Chem. 285 24466-76 PubMed GONUTS page

[PMID:21712997-8] Schmutz, I et al. (2011) Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock. PLoS ONE 6 e21325 PubMed GONUTS page

[PMID:11739654-9] 9.0 ^9.1 Trinkle-Mulcahy, L et al. (2001) Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells. J. Cell. Sci. 114 4219-28 PubMed GONUTS page

[PMID:21873635-10] 10.0 ^10.1 ^10.2 ^10.3 ^10.4 ^10.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:22801782-11] Wurzenberger, C et al. (2012) Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J. Cell Biol. 198 173-83 PubMed GONUTS page

[PMID:16262633-12] 12.0 ^12.1 ^12.2 Liu, F et al. (2005) Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur. J. Neurosci. 22 1942-50 PubMed GONUTS page

[PMID:8392016-13] 13.0 ^13.1 Song, Q et al. (1993) Cloning and characterization of a human protein phosphatase 1-encoding cDNA. Gene 129 291-5 PubMed GONUTS page

[PMID:10640627-14] Gong, CX et al. (2000) Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain. Brain Res. 853 299-309 PubMed GONUTS page

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HUMAN:PP1A

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