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Category:GO:0004638 ! phosphoribosylaminoimidazole carboxylase activity
name: phosphoribosylaminoimidazole carboxylase activity
namespace: molecular_function
def: "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)." [EC:4.1.1.21, RHEA:10795]
subset: gosubset_prok
synonym: "1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity" EXACT [EC:4.1.1.21]
synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]" RELATED [EC:4.1.1.21]
synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity" EXACT [EC:4.1.1.21]
synonym: "5-amino-1-ribosylimidazole 5-phosphate carboxylase activity" EXACT [EC:4.1.1.21]
synonym: "5-phosphoribosyl-5-aminoimidazole carboxylase activity" EXACT [EC:4.1.1.21]
synonym: "ADE2" RELATED [EC:4.1.1.21]
synonym: "AIR carboxylase activity" EXACT [EC:4.1.1.21]
synonym: "class II PurE" RELATED [EC:4.1.1.21]
xref: EC:4.1.1.21
xref: KEGG:R04209
xref: MetaCyc:AIRCARBOXY-RXN
xref: Reactome:REACT_105892 "AIR + CO2 => CAIR, Taeniopygia guttata"
xref: Reactome:REACT_108287 "AIR + CO2 => CAIR, Sus scrofa"
xref: Reactome:REACT_110684 "AIR + CO2 => CAIR, Gallus gallus"
xref: Reactome:REACT_110707 "AIR + CO2 => CAIR, Bos taurus"
xref: Reactome:REACT_115900 "5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR), Gallus gallus"
xref: Reactome:REACT_28954 "AIR + CO2 => CAIR, Xenopus tropicalis"
xref: Reactome:REACT_29663 "AIR + CO2 => CAIR, Escherichia coli"
xref: Reactome:REACT_31451 "AIR + CO2 => CAIR, Drosophila melanogaster"
xref: Reactome:REACT_589 "AIR + CO2 => CAIR, Homo sapiens"
xref: Reactome:REACT_78332 "AIR + CO2 => CAIR, Staphylococcus aureus N315"
xref: Reactome:REACT_78854 "AIR + CO2 => CAIR, Caenorhabditis elegans"
xref: Reactome:REACT_81065 "AIR + CO2 => CAIR, Danio rerio"
xref: Reactome:REACT_87755 "AIR + CO2 => CAIR, Rattus norvegicus"
xref: Reactome:REACT_94416 "AIR + CO2 => CAIR, Canis familiaris"
xref: Reactome:REACT_97372 "AIR + CO2 => CAIR, Mus musculus"
xref: RHEA:10795
is_a: GO:0016831 ! carboxy-lyase activity
AmiGO
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