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User:Evazquez
CACAO Spring 2014
My Annotations
| Status | Page | Date/Time | GO Term (Aspect) | Reference | Evidence | Notes | Links |
|---|---|---|---|---|---|---|---|
| ? | 2014-02-02 15:31:15 CST | GO:0060298 positive regulation of sarcomere organization (Figure 1 (A, B) shows that injection of Danio rerio with triple tnnt morpholino oligonucleotides (tnnt2c, tnnt3a, tnnt3b)had a decreased showing of myofibril striation at 28 hours post fertilization. This shows the necessity of troponin-based genes for muscle differentiation.) | PMID:21245197 | IGI: Inferred from Genetic Interaction Zfin:ZDB-GENE-000322-3
Zfin:ZDB-GENE-030520-2 UniProtKB:Q7ZZW4 UniProtKB:Q9I8U9 | challenge | ||
| ? | 2014-02-02 16:03:29 CST | GO:0060298 positive regulation of sarcomere organization (When comparing the control and the experimental triple tnnt (tnnt2c, tnnt3a, tnnt3b) morpholino oligonucleotide-injected panels in Figure 1 (C' and D'), it is seen that at 48 hours post-fertilization, T12 (a titin epitope) is delocalized from normal Z line locations.) | PMID:21245197 | IGI: Inferred from Genetic Interaction Zfin:ZDB-GENE-000322-3
Zfin:ZDB-GENE-030520-2 UniProtKB:Q7ZZW4_DANRE UniProtKB:Q9I8U9_DANRE | challenge | ||
| ? | 2014-02-02 16:03:30 CST | GO:0060298 positive regulation of sarcomere organization (When comparing the control and the experimental triple tnnt (tnnt2c, tnnt3a, tnnt3b) morpholino oligonucleotide-injected panels in Figure 1 (C'' and D''), it is seen that at 48 hours post-fertilization, actin is delocalized from normal muscle striations to be randomly dispersed in muscle.) | PMID:21245197 | IGI: Inferred from Genetic Interaction Zfin:ZDB-GENE-000322-3
Zfin:ZDB-GENE-030520-2 UniProtKB:Q7ZZW4_DANRE UniProtKB:Q9I8U9_DANRE | challenge | ||
| ? | 2014-02-02 16:13:11 CST | GO:0060299 negative regulation of sarcomere organization (By disrupting the expression of different members of the troponin T family, and comparing wildtype and mutant zebrafish, it has been concluded that troponin is required for normal myofibrillogenesis. In the absence of troponin, sarcomeres do not form, instead stacks of thick filaments, expanded Z lines and aggregates of filamentous actin can be observed. Methods used to display the results include transmission electron microscopy, immunofluorescence assays, electron micrographs, electron microscopy and immunostaining.) | PMID:21245197 | IMP: Inferred from Mutant Phenotype | challenge | ||
| ? | 2014-02-02 16:26:25 CST | GO:0060298 positive regulation of sarcomere organization (In Figure 1 (E and F), Danio rerio is stained to show that at 48 hours post-fertilization T11 (a titin epitope)is delocalized from the I-band/A-band portions in muscle to become scattered in the cytoplasm. This is after triple tnnt (tnnt2c, tnnt3a, tnnt3b) morpholino oligonucleotide injection.) | PMID:21245197 | IGI: Inferred from Genetic Interaction Zfin:ZDB-GENE-000322-3
Zfin:ZDB-GENE-030520-2 UniProtKB:Q7ZZW4_DANRE UniProtKB:Q9I8U9_DANRE | challenge | ||
| ? | 2014-02-02 16:26:25 CST | GO:0060298 positive regulation of sarcomere organization (In Figure 1 (G and H), Danio rerio is stained to show that at 48 hours post-fertilization myomesin (an endline protein that is found in the M-band of muscle) is delocalized to become scattered in the cytoplasm of muscle. This is after triple tnnt (tnnt2c, tnnt3a, tnnt3b) morpholino oligonucleotide injection.) | 21245197:21245197 | IGI: Inferred from Genetic Interaction Zfin:ZDB-GENE-000322-3
Zfin:ZDB-GENE-030520-2 UniProtKB:Q7ZZW4_DANRE UniProtKB:Q9I8U9_DANRE | challenge | ||
| ? | 2014-02-02 16:52:45 CST | GO:0060298 positive regulation of sarcomere organization (In Figure 1 (I and J), Danio rerio is stained to show that at 48 hours post-fertilization tropomyosin (a protein that is important in actin filaments) is organizational control is significantly delocalized from the thin actin filaments after triple tnnt (tnnt2c, tnnt3a, tnnt3b) morpholino oligonucleotide injection.) | PMID:21245197 | IGI: Inferred from Genetic Interaction Zfin:ZDB-GENE-000322-3
Zfin:ZDB-GENE-030520-2 UniProtKB:Q7ZZW4_DANRE UniProtKB:Q9I8U9_DANRE | challenge |
acceptable:0
unacceptable:7
requires_changes:0
flagged:0
Annotations challenged by Evazquez
| Status | Author,Group | Page | GO Term (Aspect) | Reference | Evidence | Links | Page history |
|---|
0 annotations fixed by Evazquez
