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Cacao

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GO:0000496base pairingPMID:28153577ECO:0000256 match to sequence model evidence used in automatic assertionMolecular Function
Figure 2. Phylogenetic tree. The phylogenetic tree was generated in MEGA6 using the Neigbour-joining method. The percentages of replicate trees in which the associated taxa clustered together in bootrstrap tests (10000 replicates) are shown next to the branches. The GenBank accession Nos. of GnRHRs are as follows: African cichlid [AAK29745; NP_001273217]; Atlantic croaker [ABB97085]; Black porgy [AAV71128]; chub mackerel [ANC48011]; common octopus [Q2V2K5]; European seabass [CAD11992]; Greater amberjack [CAB65407]; house mouse [NP_034453]; human [NP_000397]; medaka [NP_001098352; NP_001098392; NP_001098393]; Nile tilapia [BAC77240; NP_001266689]; pejerrey [ABI75336; ABI75337]; Red seabream [BAM17648]; Rhesus monkey [NP_001028014] and striped bass [AAF28464]. Octopus GnRHR was used as an outgroup.

cmGnRHR1 clustered under Type IIB receptors which involve in reproduction and gonadotropic function control Organism: Scomber Japonicus Protein: Gonadotropin Releasing Hormone Receptor1

complete
This annotation made on page: SCOJP:A0A161I6V9
By: Albert (group Team GOinUP) on 2019-09-27 10:05:36 CDT.



TeamPoints
Team GOinUP5




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Private
Assessment
Jrr2019-11-12 14:54:31 CSTYou need to be an instructor to view these notes.Acceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Private
Assessment
Jrr2019-11-12 14:52:09 CSTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Go term
Evidence
Notes
Unique/Original
Public
Assessment
DanielRenfro2019-11-05 07:30:19 CST

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004968 gonadotropin-releasing hormone receptor activity PMID:28153577 ECO:0001805 luciferase reporter gene assay evidence F Figure 3. Ligand selectivity of chub mackerel pituitary GnRH receptor, cmGnRHR1 with CRE-Luc.

Synthetic GnRHa peptides showed potency to cmGnRHR1 and leads to secretion of LH (Figure 4.)

Protein: chub mackerel Gonadotropin Releasing Hormone Receptor1 (cmGnRHR1)||complete
CACAO 13783

on SCOJP:A0A161I6V9
Flagged
Public
Assessment
DanielRenfro2019-11-05 07:03:22 CST

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004968 gonadotropin-releasing hormone receptor activity PMID:28153577 ECO:0001805 luciferase reporter gene assay evidence F Figure 3. Ligand selectivity of chub mackerel pituitary GnRH receptor, cmGnRHR1 with CRE-Luc.

Synthetic GnRHa peptides showed potency to cmGnRHR1

Supporting data includes in vitro test on secretion of LH from pituitary cells of immature adult female chub mackerel using cmGnRH1, cmGnRH2 and cmGnRH3 (Figure 4) showing GnRH ligands are not only capable of binding to receptor (cmGnRHR) but also capable of releasing LH

Protein: chub mackerel Gonadotropin Releasing Hormone Receptor1 (cmGnRHR1)||complete
CACAO 13783

on SCOJP:A0A161I6V9
Flagged
Private
Assessment
CRoss20082019-10-14 13:43:31 CDTYou need to be an instructor to view these notes.Requires Changes
Evidence
Public
Assessment
DanielRenfro2019-10-11 09:21:50 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004968 gonadotropin-releasing hormone receptor activity PMID:28153577 ECO:0007826 phylogenetic evidence used in automatic assertion F Figure 2. Phylogenetic tree. The phylogenetic tree was generated in MEGA6 using the Neigbour-joining method. The percentages of replicate trees in which the associated taxa clustered together in bootrstrap tests (10000 replicates) are shown next to the branches. The GenBank accession Nos. of GnRHRs are as follows: African cichlid [AAK29745; NP_001273217]; Atlantic croaker [ABB97085]; Black porgy [AAV71128]; chub mackerel [ANC48011]; common octopus [Q2V2K5]; European seabass [CAD11992]; Greater amberjack [CAB65407]; house mouse [NP_034453]; human [NP_000397]; medaka [NP_001098352; NP_001098392; NP_001098393]; Nile tilapia [BAC77240; NP_001266689]; pejerrey [ABI75336; ABI75337]; Red seabream [BAM17648]; Rhesus monkey [NP_001028014] and striped bass [AAF28464]. Octopus GnRHR was used as an outgroup.

cmGnRHR1 clustered under Type IIB receptors which involve in reproduction and gonadotropic function control Organism: Scomber Japonicus Protein: Gonadotropin Releasing Hormone Receptor1||complete
CACAO 13783

on SCOJP:A0A161I6V9
Flagged
Public
Assessment
DanielRenfro2019-10-11 08:10:51 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000496 base pairing PMID:28153577 ECO:0007826 phylogenetic evidence used in automatic assertion F Figure 2. Phylogenetic tree. The phylogenetic tree was generated in MEGA6 using the Neigbour-joining method. The percentages of replicate trees in which the associated taxa clustered together in bootrstrap tests (10000 replicates) are shown next to the branches. The GenBank accession Nos. of GnRHRs are as follows: African cichlid [AAK29745; NP_001273217]; Atlantic croaker [ABB97085]; Black porgy [AAV71128]; chub mackerel [ANC48011]; common octopus [Q2V2K5]; European seabass [CAD11992]; Greater amberjack [CAB65407]; house mouse [NP_034453]; human [NP_000397]; medaka [NP_001098352; NP_001098392; NP_001098393]; Nile tilapia [BAC77240; NP_001266689]; pejerrey [ABI75336; ABI75337]; Red seabream [BAM17648]; Rhesus monkey [NP_001028014] and striped bass [AAF28464]. Octopus GnRHR was used as an outgroup.

cmGnRHR1 clustered under Type IIB receptors which involve in reproduction and gonadotropic function control Organism: Scomber Japonicus Protein: Gonadotropin Releasing Hormone Receptor1||complete
CACAO 13783

on SCOJP:A0A161I6V9
Flagged
Private
Assessment
CRoss20082019-09-30 21:00:59 CDTYou need to be an instructor to view these notes.Requires Changes
Evidence