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Cacao

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GO:0043138DNA helicase activityPMID:25246477IDA: Inferred from Direct Assay F
This annotation made on page: BACSU:A3F475
By: Jkwan2 (group Team Asian persuasian) on 2016-04-19 11:09:41 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeIac1,
Team Purple B
2016-04-18 00:20:38 CDT

Fig. 5 specifically showcases the polarity of the recQ helicase. Simply having DNA helicase activity as the GO term is not accurate enough based upon this figure. "The RecQ[Bs] helicase unwound only the 3′-overhung dsDNA substrate (Fig. 5), indicating that RecQ[Bs] is a unidirectional helicase with a 3′→5′ polarity." Therefore, the more accurate GO ID should be GO:0043138 which is the GO term "3'-5' DNA helicase activity".

7
Private
Assessment
Suzialeksander2016-06-13 16:04:54 CDTYou need to be an instructor to view these notes.Updated by Instructor
Public
Assessment
Suzialeksander2016-04-28 16:48:38 CDT

Iac1 gets credit for the annotation.

Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Private
Assessment
Suzialeksander2016-04-28 16:47:42 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2016-04-19 11:09:41 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0043138 DNA helicase activity PMID:25246477 IDA: Inferred from Direct Assay F Figure 5. show RecQ is a 3'to5' DNA helicase. It unwind NDA substrate with 3' single stranded region. complete
CACAO 11685
on BACSU:A3F475
Flagged