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Category:MichSt14A 6

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableLISMN:A3RI35Deasonni, MichSt14A 62014-04-05 12:51:43 CDTGO:0044650 adhesion of symbiont to host cell (P)PMID:18599819ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 3 shows listeria monocytogenes cells carrying a deletion mutation of the ispC gene have decreased adherence to non-phagocytic eukaryotic cell lines as compared to the wild-type strain.

challenge
unacceptableLISSS:D3UPC7Deasonni, MichSt14A 62014-04-03 13:46:20 CDTGO:0044406 adhesion to host (Fig 4 shows that fbpA deletion mutants of listeria monocytogenes have decreased adhesion to hepatocytes and macrophages, also that mutants over-expressing fbpA had adhesion similar to the wild-type.)PMID:23586629IMP: Inferred from Mutant Phenotype
challenge
updatedbyinstructorLISMN:A0A0B8R8Z5Deasonni, MichSt14A 62014-04-03 12:35:06 CDTGO:1900233 positive regulation of single-species biofilm formation on inanimate substrate (P)PMID:23562858ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 1 shows that strains of listeria monocytogenes with a deletion of gltC have decreased bio-film formation as compared to the wild-type strain and that a gltC complement strain has bio-film formation similar to the wild-type.

challenge
updatedbyinstructorLISMN:A0A0E1R8M9Deasonni, MichSt14A 62014-04-03 12:27:02 CDTGO:1900233 positive regulation of single-species biofilm formation on inanimate substrate (P)PMID:23562858ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 1 shows a mutant strain of listeria monocytogenes with a deletion of gltB has decreased bio-film formation as compared to wild-type in a bio-film formation assay.

challenge
acceptableLISMN:Q4TVQ0Deasonni, MichSt14A 62014-04-03 11:09:52 CDTGO:1900233 positive regulation of single-species biofilm formation on inanimate substrate (P)PMID:20511507ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 2(a) shows that mutants with defective prfA gene showed reduced bio-film formation on PVC plates when compared to wild-type across a range of temperatures.

2(c) shows that complementation of the defective gene results in a return to wild-type levels of bio-film formation.

challenge

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