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Category:GO:1903231 ! mRNA base-pairing post-transcriptional repressor activity
name: mRNA base-pairing post-transcriptional repressor activity
namespace: molecular_function
alt_id: GO:0150100
def: "A post-transcriptional repressor activity that acts by base-pairing with an mRNA to prevent gene expression. The binding can result in targeting the mRNA for degradation or interfering with mRNA translation resulting in post-transcriptional gene silencing." [GOC:BHF, GOC:BHF_miRNA, GOC:ha, GOC:vw, PMID:18197166, PMID:20533884]
comment: This term is intended for ncRNAs that act by base-pairing with a target mRNA.
synonym: "mRNA base-pairing posttranscriptional repressor activity" EXACT []
synonym: "mRNA base-pairing translational repressor activity" NARROW []
synonym: "mRNA binding involved in cosuppression" RELATED [GOC:TermGenie]
synonym: "mRNA binding involved in post-transcriptional gene silencing" EXACT [GOC:TermGenie]
synonym: "mRNA binding involved in posttranscriptional gene silencing" RELATED []
synonym: "mRNA binding involved in PTGS" RELATED [GOC:TermGenie]
synonym: "mRNA binding involved in quelling" EXACT [GOC:TermGenie]
synonym: "mRNA binding translation repressor activity" RELATED []
synonym: "translational inhibitor activity via mRNA base-pairing" NARROW []
is_a: GO:1990825 ! sequence-specific mRNA binding
relationship: part_of: GO:0035194 ! regulatory ncRNA-mediated post-transcriptional gene silencing
AmiGO
<GOterm>GO:1903231</GOterm>
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