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Category:GO:0036317 ! tyrosyl-RNA phosphodiesterase activity

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DAG for GO:0036317id: GO:0036317

name: tyrosyl-RNA phosphodiesterase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis." [GOC:bf, GOC:sp, PMID:21408223, PMID:22908287]
synonym: "unlinkase activity" EXACT [PMID:21408223]
synonym: "uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity" EXACT [PMID:21408223]
synonym: "VPg unlinkase activity" EXACT [GOC:sp, PMID:21408223, PMID:22908287]
synonym: "Y-pUpN PDE activity" EXACT [PMID:21408223]
is_a: GO:0008081 ! phosphoric diester hydrolase activity
is_a: GO:0140098 ! catalytic activity, acting on RNA

AmiGO <GOterm>GO:0036317</GOterm>
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