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Category:GO:0016213 ! linoleoyl-CoA desaturase activity
name: linoleoyl-CoA desaturase activity
namespace: molecular_function
def: "Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-CoA and add a fourth double bond (a (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA)." [EC:1.14.19.3, PMID:12713571, PMID:7212717]
synonym: "delta(6)-acyl CoA desaturase activity" BROAD []
synonym: "delta(6)-desaturase activity" BROAD []
synonym: "delta(6)-fatty acyl-CoA desaturase activity" BROAD []
synonym: "delta6-acyl CoA desaturase activity" RELATED [EC:1.14.19.3]
synonym: "delta6-desaturase activity" RELATED [EC:1.14.19.3]
synonym: "delta6-fatty acyl-CoA desaturase activity" RELATED [EC:1.14.19.3]
synonym: "fatty acid 6-desaturase activity" BROAD []
synonym: "fatty acid delta(6)-desaturase activity" BROAD []
synonym: "fatty acid delta6-desaturase activity" RELATED [EC:1.14.19.3]
synonym: "linoleate desaturase activity" RELATED []
synonym: "linoleic acid desaturase activity" RELATED []
synonym: "linoleic desaturase activity" RELATED []
synonym: "linoleoyl CoA desaturase activity" EXACT []
synonym: "linoleoyl-coenzyme A desaturase activity" EXACT []
synonym: "long-chain fatty acid delta(6)-desaturase activity" BROAD []
synonym: "long-chain fatty acid delta6-desaturase activity" RELATED [EC:1.14.19.3]
xref: EC:1.14.19.3
xref: MetaCyc:1.14.19.3-RXN
is_a: GO:0016215 ! acyl-CoA desaturase activity
AmiGO
<GOterm>GO:0016213</GOterm>
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