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Category:GO:0004503 ! tyrosinase activity
name: tyrosinase activity
namespace: molecular_function
def: "Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates." [PMID:4965136, RHEA:18117]
comment: In mammals, L-DOPA can act as a cofactor for the catalyzed reaction; therefore in some resources L-DOPA is shown on both sides of the reaction. GO:0004503 describes the monooxygenation of the monophenol, L-tyrosine. For oxidation of diphenols (including L-DOPA and dopamine), consider instead the term 'catechol oxidase activity ; GO:0004097' and its children.
synonym: "catecholase" RELATED []
synonym: "chlorogenic acid oxidase activity" RELATED []
synonym: "chlorogenic oxidase activity" RELATED []
synonym: "cresolase activity" RELATED [EC:1.14.18.1]
synonym: "dopa oxidase" RELATED []
synonym: "L-tyrosine monooxygenase activity" EXACT [GOC:bf]
synonym: "monophenol monooxidase activity" RELATED []
synonym: "monophenol monooxygenase activity" EXACT [EC:1.14.18.1]
synonym: "monophenol oxidase activity" RELATED [EC:1.14.18.1]
synonym: "monophenol oxygenase" EXACT [EC:1.14.18.1, PMID:2494997]
synonym: "monophenolase activity" RELATED []
synonym: "N-acetyl-6-hydroxytryptophan oxidase activity" RELATED [EC:1.14.18.1]
synonym: "o-diphenol oxidase activity" RELATED []
synonym: "o-diphenol oxidoreductase" RELATED []
synonym: "o-diphenol:O2 oxidoreductase activity" RELATED [EC:1.14.18.1]
synonym: "phenol oxidase activity" BROAD []
synonym: "phenolase activity" BROAD [EC:1.14.18.1]
synonym: "prophenol oxidase activity" RELATED [GOC:sart]
synonym: "prophenoloxidase activity" RELATED []
synonym: "pyrocatechol oxidase" BROAD []
synonym: "tyrosine-dopa oxidase activity" RELATED [EC:1.14.18.1]
xref: EC:1.14.18.1
xref: MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN
is_a: GO:0016716 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
AmiGO
<GOterm>GO:0004503</GOterm>
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This category has the following 2 subcategories, out of 2 total.
Pages in category "GO:0004503 ! tyrosinase activity"
The following 4 pages are in this category, out of 4 total.
