CHICK:SPP2B

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	SPPL2B
Protein Name(s)	Signal peptide peptidase-like 2B SPP-like 2B SPPL2b
External Links
UniProt	Q5F383
EMBL	AJ851767
RefSeq	NP_001026104.1
UniGene	Gga.22754
ProteinModelPortal	Q5F383
STRING	9031.ENSGALP00000000586
MEROPS	A22.004
PaxDb	Q5F383
GeneID	420056
KEGG	gga:420056
CTD	56928
eggNOG	NOG250196
HOGENOM	HOG000231496
HOVERGEN	HBG024193
InParanoid	Q5F383
KO	K09597
PhylomeDB	Q5F383
NextBio	20823021
PRO	PR:Q5F383
Proteomes	UP000000539
GO	GO:0010008 GO:0030660 GO:0071458 GO:0071556 GO:0005765 GO:0005886 GO:0042500 GO:0042803 GO:0006509 GO:0031293 GO:0050776
InterPro	IPR007369 IPR006639 IPR003137
PANTHER	PTHR12174
Pfam	PF02225 PF04258
SMART	SM00730

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	C	Seeded From UniProt	complete
part_of	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	C	Seeded From UniProt	complete
involved_in	GO:0050776	regulation of immune response	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	F	Seeded From UniProt	complete
NOT\|enables	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	F	Seeded From UniProt	complete
enables	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	F	Seeded From UniProt	complete
involved_in	GO:0031293	membrane protein intracellular domain proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	P	Seeded From UniProt	complete
part_of	GO:0030660	Golgi-associated vesicle membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	C	Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	C	Seeded From UniProt	complete
involved_in	GO:0006509	membrane protein ectodomain proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	C	Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8TCT7	C	Seeded From UniProt	complete
part_of	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000256204 UniProtKB:Q8IUH8 UniProtKB:Q8TCT7 UniProtKB:Q8TCT8	C	Seeded From UniProt	complete
part_of	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000256204 UniProtKB:Q8IUH8 UniProtKB:Q8TCT7 UniProtKB:Q8TCT8	C	Seeded From UniProt	complete
enables	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000256204 UniProtKB:Q8TCT7 UniProtKB:Q8TCT8	F	Seeded From UniProt	complete
involved_in	GO:0033619	membrane protein proteolysis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000256204 UniProtKB:Q8TCT7 UniProtKB:Q8TCT8	P	Seeded From UniProt	complete
part_of	GO:0030660	Golgi-associated vesicle membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000256204 UniProtKB:Q8TCT7 UniProtKB:Q8TCT8	C	Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1913802 PANTHER:PTN000256204 UniProtKB:Q8TCT7	C	Seeded From UniProt	complete
enables	GO:0004190	aspartic-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006639 InterPro:IPR007369	F	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006639 InterPro:IPR007369	C	Seeded From UniProt	complete
involved_in	GO:0031293	membrane protein intracellular domain proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033149	P	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0005764	lysosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0458	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0333	C	Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0157	C	Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0100	C	Seeded From UniProt	complete
part_of	GO:0000139	Golgi membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0134	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:SPP2B

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