THEMA:CHEA

Species (Taxon ID)	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099). (243274)
Gene Name(s)	cheA
Protein Name(s)	Chemotaxis protein CheA
External Links
UniProt	Q56310
EMBL	U30501 AE000512
PIR	D72346
RefSeq	NP_228511.1 YP_007977052.1 YP_008990329.1
PDB	1B3Q 1I58 1I59 1I5A 1I5B 1I5C 1I5D 1TQG 1U0S 2CH4 2LD6 3UR1 4JPB
PDBsum	1B3Q 1I58 1I59 1I5A 1I5B 1I5C 1I5D 1TQG 1U0S 2CH4 2LD6 3UR1 4JPB
ProteinModelPortal	Q56310
SMR	Q56310
DIP	DIP-29071N
IntAct	Q56310
STRING	243274.TM0702
DNASU	898369
EnsemblBacteria	AAD35784
GeneID	18092087 898369
KEGG	tma:TM0702
PATRIC	23936322
eggNOG	COG0643
InParanoid	Q56310
KO	K03407
OMA	VQTIRVN
OrthoDB	EOG62RS8P
BRENDA	2.7.13.3
EvolutionaryTrace	Q56310
Proteomes	UP000008183
GO	GO:0005737 GO:0005524 GO:0000155 GO:0006928 GO:0006935
Gene3D	1.10.287.560 1.20.120.160 3.30.565.10 3.30.70.1110
InterPro	IPR004105 IPR002545 IPR015162 IPR003594 IPR004358 IPR008207 IPR005467 IPR009082 IPR010808
Pfam	PF01584 PF02895 PF02518 PF01627 PF07194
PRINTS	PR00344
SMART	SM00260 SM00387 SM00073
SUPFAM	SSF47226 SSF47384 SSF50341 SSF55052 SSF55874
PROSITE	PS50851 PS50109 PS50894

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0016301	kinase activity	PMID:9989504	ECO:0000255		UniProtKB:Q56310	F		Figure 1 shows a schematic design of CheA histidine kinase based upon the position of the sequence of the substrate histidine (H box) with respect to the kinase domain. CheW is shown in this design, but it is actually a coupling protein that interacts with the sensor and CheA.	complete
enables	GO:0019904	protein domain specific binding		ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q56311	F		Seeded From UniProt	complete
involved_in	GO:0018106	peptidyl-histidine phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004673	P		Seeded From UniProt	complete
involved_in	GO:0018106	peptidyl-histidine phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004673	P		Seeded From UniProt	complete
involved_in	GO:0023014	signal transduction by protein phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0000155	P		Seeded From UniProt	complete
enables	GO:0000155	phosphorelay sensor kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004105 InterPro:IPR010808 InterPro:IPR036097 InterPro:IPR037006	F		Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004105 InterPro:IPR008207 InterPro:IPR010808 InterPro:IPR036641	P		Seeded From UniProt	complete
enables	GO:0004673	protein histidine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004105 InterPro:IPR010808	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004105	C		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002545 InterPro:IPR004105 InterPro:IPR036061 InterPro:IPR037006	P		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002545 InterPro:IPR036061 InterPro:IPR036097	P		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004358	P		Seeded From UniProt	complete
enables	GO:0016772	transferase activity, transferring phosphorus-containing groups	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004358	F		Seeded From UniProt	complete
enables	GO:0004673	protein histidine kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.13.3	F		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0145	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0902	P		Seeded From UniProt	complete
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