Category:GO:0007165 ! signal transduction

name: signal transduction
namespace: biological_process
alt_id:GO:0023033
def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11]
comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.
subset: goslim_aspergillus
subset: goslim_candida
subset: goslim_generic
subset: goslim_plant
subset: gosubset_prok
synonym: "signaling cascade" NARROW []
synonym: "signaling pathway" RELATED []
synonym: "signalling cascade" NARROW []
synonym: "signalling pathway" RELATED [GOC:mah]
xref: Reactome:REACT_100624 "EGFR interacts with phospholipase C-gamma, Gallus gallus"
xref: Reactome:REACT_102354 "EGFR interacts with phospholipase C-gamma, Canis familiaris"
xref: Reactome:REACT_112130 "EGFR interacts with phospholipase C-gamma, Oryza sativa"
xref: Reactome:REACT_112549 "EGFR interacts with phospholipase C-gamma, Arabidopsis thaliana"
xref: Reactome:REACT_113151 "EGFR interacts with phospholipase C-gamma, Mycobacterium tuberculosis"
xref: Reactome:REACT_113601 "EGFR interacts with phospholipase C-gamma, Drosophila melanogaster"
xref: Reactome:REACT_113964 "EGFR interacts with phospholipase C-gamma, Bos taurus"
xref: Reactome:REACT_114657 "EGFR interacts with phospholipase C-gamma, Dictyostelium discoideum"
xref: Reactome:REACT_114690 "EGFR interacts with phospholipase C-gamma, Saccharomyces cerevisiae"
xref: Reactome:REACT_114820 "EGFR interacts with phospholipase C-gamma, Sus scrofa"
xref: Reactome:REACT_114910 "EGFR interacts with phospholipase C-gamma, Caenorhabditis elegans"
xref: Reactome:REACT_115037 "EGFR interacts with phospholipase C-gamma, Plasmodium falciparum"
xref: Reactome:REACT_115147 "EGFR interacts with phospholipase C-gamma, Schizosaccharomyces pombe"
xref: Reactome:REACT_12478 "EGFR interacts with phospholipase C-gamma, Homo sapiens"
xref: Reactome:REACT_31232 "EGFR interacts with phospholipase C-gamma, Rattus norvegicus"
xref: Reactome:REACT_78535 "EGFR interacts with phospholipase C-gamma, Xenopus tropicalis"
xref: Reactome:REACT_89740 "EGFR interacts with phospholipase C-gamma, Taeniopygia guttata"
xref: Reactome:REACT_93680 "EGFR interacts with phospholipase C-gamma, Danio rerio"
xref: Reactome:REACT_98872 "EGFR interacts with phospholipase C-gamma, Mus musculus"
xref: Wikipedia:Signal_transduction
is_a: GO:0050794 ! regulation of cellular process
is_a: GO:0051716 ! cellular response to stimulus
relationship:part_of: GO:0007154 ! cell communication
relationship:part_of: GO:0023052 ! signaling

AmiGO

Child Terms

This term has the following 42 child terms, out of 42 total.

Pages in category "GO:0007165 ! signal transduction"

The following 200 pages are in this category, out of 5,424 total.