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MOUSE:CATL1
Contents |
| Species (Taxon ID) | Mus musculus (Mouse). ([1]) | |
| Gene Name(s) | Ctsl1 (synonyms: Ctsl) | |
| Protein Name(s) | Cathepsin L1
Major excreted protein MEP p39 cysteine proteinase Cathepsin L1 heavy chain Cathepsin L1 light chain | |
| External Links | ||
| EMBL | X06086 J02583 M20495 AF121837 AF121838 AF121839 BC068163 X04392 | |
| IPI | IPI00128154 | |
| PIR | S01177 | |
| RefSeq | NP_034114.1 | |
| UniGene | Mm.930 | |
| PDB | 1MVV | |
| PDBsum | 1MVV | |
| ProteinModelPortal | P06797 | |
| SMR | P06797 | |
| STRING | P06797 | |
| MEROPS | C01.032 | |
| PRIDE | P06797 | |
| Ensembl | ENSMUST00000021933 | |
| GeneID | 13039 | |
| KEGG | mmu:13039 | |
| CTD | 13039 | |
| MGI | MGI:88564 | |
| HOGENOM | HBG746690 | |
| HOVERGEN | HBG011513 | |
| InParanoid | P06797 | |
| OMA | CEIESAV | |
| OrthoDB | EOG48PMKF | |
| PhylomeDB | P06797 | |
| BioCyc | MetaCyc:MONOMER-14812 | |
| BRENDA | 3.4.22.15 | |
| NextBio | 282928 | |
| ArrayExpress | P06797 | |
| Bgee | P06797 | |
| CleanEx | MM_CTSL | |
| Genevestigator | P06797 | |
| GermOnline | ENSMUSG00000021477 | |
| GO | GO:0009897 GO:0005764 GO:0005902 GO:0043005 GO:0005730 GO:0043204 GO:0005625 GO:0004177 GO:0004197 GO:0042393 GO:0042277 GO:0048102 GO:0009267 GO:0046697 GO:0010259 GO:0021675 GO:0006508 GO:0051384 GO:0009749 GO:0034698 GO:0014070 GO:0051789 GO:0060008 GO:0007283 GO:0048863 | |
| InterPro | IPR000169 IPR013128 IPR000668 IPR013201 | |
| PANTHER | PTHR12411 | |
| Pfam | PF08246 PF00112 | |
| PRINTS | PR00705 | |
| SMART | SM00848 SM00645 | |
| PROSITE | PS00640 PS00139 PS00639 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004177 |
aminopeptidase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
F |
Seeded From UniProt |
|||
| GO:0004177 |
aminopeptidase activity |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded From UniProt |
||||
| GO:0004197 |
cysteine-type endopeptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004197 |
cysteine-type endopeptidase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
F |
Seeded From UniProt |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005625 |
soluble fraction |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0005625 |
soluble fraction |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0005730 |
nucleolus |
NAS: Non-traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0005764 |
lysosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005764 |
lysosome |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0005764 |
lysosome |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0158 |
C |
Seeded From UniProt |
|||
| GO:0005764 |
lysosome |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0005773 |
vacuole |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0005773 |
vacuole |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0005902 |
microvillus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0005902 |
microvillus |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0006508 |
proteolysis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006508 |
proteolysis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006508 |
proteolysis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0006508 |
proteolysis |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0006508 |
proteolysis |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0007154 |
cell communication |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0007154 |
cell communication |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0007283 |
spermatogenesis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0007283 |
spermatogenesis |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0008233 |
peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008234 |
cysteine-type peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008234 |
cysteine-type peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008234 |
cysteine-type peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008234 |
cysteine-type peptidase activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0008584 |
male gonad development |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0008584 |
male gonad development |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0009267 |
cellular response to starvation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0009267 |
cellular response to starvation |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0009749 |
response to glucose stimulus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0009749 |
response to glucose stimulus |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0009897 |
external side of plasma membrane |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0009897 |
external side of plasma membrane |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0010259 |
multicellular organismal aging |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0010259 |
multicellular organismal aging |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0014070 |
response to organic cyclic compound |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0014070 |
response to organic cyclic compound |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0016787 |
hydrolase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0021675 |
nerve development |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0021675 |
nerve development |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0030141 |
stored secretory granule |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0030984 |
kininogen binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
F |
Seeded From UniProt |
|||
| GO:0034698 |
response to gonadotropin stimulus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0034698 |
response to gonadotropin stimulus |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0042277 |
peptide binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
F |
Seeded From UniProt |
|||
| GO:0042277 |
peptide binding |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded From UniProt |
||||
| GO:0042393 |
histone binding |
NAS: Non-traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0043005 |
neuron projection |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0043005 |
neuron projection |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0043204 |
perikaryon |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0043204 |
perikaryon |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0045177 |
apical part of cell |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
C |
Seeded From UniProt |
|||
| GO:0046697 |
decidualization |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0046697 |
decidualization |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0048102 |
autophagic cell death |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0048102 |
autophagic cell death |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0048863 |
stem cell differentiation |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0051384 |
response to glucocorticoid stimulus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0051384 |
response to glucocorticoid stimulus |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0060008 |
Sertoli cell differentiation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025462 |
P |
Seeded From UniProt |
|||
| GO:0060008 |
Sertoli cell differentiation |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0060441 |
epithelial tube branching involved in lung morphogenesis |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0030141 |
stored secretory granule |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0045177 |
apical part of cell |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0019059 |
initiation of viral infection |
IMP: Inferred from Mutant Phenotype |
P |
Fig. 1C and Fig. 1D |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Cheon YP et al. (2004) Induction of cytotoxic T-lymphocyte antigen-2beta, a cysteine protease inhibitor in decidua: a potential regulator of embryo implantation. J Biol Chem 279: 10357-63 PubMed GONUTS page
- ↑ Konjar S et al. (2010) Increased nucleolar localization of SpiA3G in classically but not alternatively activated macrophages. FEBS Lett 584: 2201-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Duncan EM et al. (2008) Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell 135: 284-94 PubMed GONUTS page
- ↑ Lü J et al. (2007) Cathespin H is an Fgf10 target involved in Bmp4 degradation during lung branching morphogenesis. J Biol Chem 282: 22176-84 PubMed GONUTS page
- ↑ Chandran K et al. (2005) Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308: 1643-5 PubMed GONUTS page
