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Category:GO:0048102 ! autophagic cell death
name: autophagic cell death
namespace: biological_process
def: "A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells." [GOC:mah, PMID:18846107]
synonym: "autophagic death" BROAD []
synonym: "programmed cell death by autophagy" EXACT []
synonym: "type II programmed cell death" RELATED [GOC:sl]
is_a: GO:0012501 ! programmed cell death
AmiGO
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