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DANRE:Q9DD89
Contents
| Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
| Gene Name(s) | ctsd (ECO:0000313 with ZFIN:ZDB-GENE-010131-8) (synonyms: cathepsin D (ECO:0000313 with EMBL:CAC20111.1)) | |
| Protein Name(s) | Cathepsin D enzyme (ECO:0000313 with EMBL:CAC20111.1) | |
| External Links | ||
| UniProt | Q9DD89 | |
| EMBL | AJ278268 | |
| RefSeq | NP_571785.1 | |
| UniGene | Dr.19238 | |
| ProteinModelPortal | Q9DD89 | |
| SMR | Q9DD89 | |
| MEROPS | A01.010 | |
| PRIDE | Q9DD89 | |
| GeneID | 65225 | |
| KEGG | dre:65225 | |
| CTD | 1509 | |
| ZFIN | ZDB-GENE-010131-8 | |
| HOGENOM | HOG000197681 | |
| HOVERGEN | HBG000482 | |
| KO | K01379 | |
| PhylomeDB | Q9DD89 | |
| NextBio | 20902022 | |
| Bgee | Q9DD89 | |
| GO | GO:0004190 GO:0061061 GO:0009617 GO:0003406 | |
| Gene3D | 2.40.70.10 | |
| InterPro | IPR001461 IPR001969 IPR012848 IPR021109 | |
| PANTHER | PTHR13683 | |
| Pfam | PF07966 PF00026 | |
| PRINTS | PR00792 | |
| SUPFAM | SSF50630 | |
| PROSITE | PS00141 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000314 |
F |
Figure 3 |
complete | |||||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061061 |
muscle structure development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-110722-1 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009617 |
response to bacterium |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0003406 |
retinal pigment epithelium development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-110722-1 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030163 |
protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000201569 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000190503 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88562 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000196689 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001461 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001461 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000415937 |
F |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Follo, C et al. (2011) Knock-down of cathepsin D affects the retinal pigment epithelium, impairs swim-bladder ontogenesis and causes premature death in zebrafish. PLoS ONE 6 e21908 PubMed GONUTS page
- ↑ Follo, C et al. (2013) Knockdown of cathepsin D in zebrafish fertilized eggs determines congenital myopathy. Biosci. Rep. 33 e00034 PubMed GONUTS page
- ↑ Meijer, AH et al. (2005) Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection. Mol. Immunol. 42 1185-203 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
