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YEAST:LSB1

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0034316

negative regulation of Arp2/3 complex-mediated actin nucleation

PMID:23577202

ECO:0000314

P

figure 2 show that purified Lsb1 and Lsb2 full-length proteins had an inhibitory activity on Las17-dependent actin polymerization in vitro. These results were further confirmed by measuring the KD constants of their interaction with Las17.

complete
CACAO 7819

public

GO:0030837

negative regulation of actin filament polymerization

PMID:23577202

ECO:0000021

P

Figure 2 gives evidence of Lsb1 and Lsb2 inhibiting Las17. Figure 4 shows Lsb1 and Lsb2 are colocalized with Las17, a protein involved in actin polymerization.

Missing: with/from
CACAO 8078

protected

part_of

GO:0005634

nucleus

PMID:14562095

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:22842922

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:22842922

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:14562095

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:11914276

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0034316

negative regulation of Arp2/3 complex-mediated actin nucleation

PMID:23577202

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0034316

negative regulation of Arp2/3 complex-mediated actin nucleation

PMID:23577202

ECO:0000353

physical interaction evidence used in manual assertion

SGD:S000005707

P

Seeded From UniProt

complete

protected

involved_in

GO:0034316

negative regulation of Arp2/3 complex-mediated actin nucleation

PMID:23577202

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0030479

actin cortical patch

PMID:23577202

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:23577202

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:1900027

regulation of ruffle assembly

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346118
PANTHER:PTN000401752

P

Seeded From UniProt

complete

protected

involved_in

GO:0051666

actin cortical patch localization

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001037916
SGD:S000001058
SGD:S000002968

P

Seeded From UniProt

complete

protected

involved_in

GO:0051017

actin filament bundle assembly

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001037916
SGD:S000001058

P

Seeded From UniProt

complete

protected

enables

GO:0051015

actin filament binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001037916
SGD:S000001058

F

Seeded From UniProt

complete

protected

enables

GO:0035091

phosphatidylinositol binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000401752
UniProtKB:Q96HL8

F

Seeded From UniProt

complete

protected

part_of

GO:0032587

ruffle membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000401752
UniProtKB:Q96HL8

C

Seeded From UniProt

complete

protected

part_of

GO:0030479

actin cortical patch

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001037916
SGD:S000001058
SGD:S000003368

C

Seeded From UniProt

complete

protected

part_of

GO:0005856

cytoskeleton

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

part_of

GO:0030479

actin cortical patch

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0008

C

Seeded From UniProt

complete




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