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TableEdit
KLEPN:BLAN1
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| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
public |
GO:0046677 |
response to antibiotic |
PMID:19770275 |
ECO:0000314 |
P |
Table 1: bla(NDM-1) from K. pneumoniae was inserted into E. coli strains, conferring resistance to several antibiotics. |
complete | ||||
|
public |
GO:0008800 |
beta-lactamase activity |
PMID:19770275 |
ECO:0000314 |
F |
Table 2 compares NDM-1's antibiotic kinetics to other metallo beta-lactamases in K. pneumoniae and shows that the New Delhi metallo beta-lactamase has very little in common comparatively to the other MBLs. Specifically that NDM-1 shows higher affinity for cephalosporins than IMP-1 and VIM-2 given by its lower Km value. |
complete | ||||
|
protected |
enables |
GO:0008270 |
zinc ion binding |
PMID:25815530 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0008270 |
zinc ion binding |
PMID:22713171 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0008800 |
beta-lactamase activity |
PMID:19770275 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0017001 |
antibiotic catabolic process |
PMID:19770275 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0008800 |
beta-lactamase activity |
GO_REF:0000003 |
ECO:0000501 |
evidence used in automatic assertion |
EC:3.5.2.6 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0042597 |
periplasmic space |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0574 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0016787 |
hydrolase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0378 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0046677 |
response to antibiotic |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0046 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0046872 |
metal ion binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0479 |
F |
Seeded From UniProt |
complete |
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