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STRVZ:Q5U913

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Species (Taxon ID) Streptomyces venezuelae. (54571)
Gene Name(s) jadH (ECO:0000313 with EMBL:AAV52248.1)
Protein Name(s) JadH (ECO:0000313 with EMBL:AAV52248.1)
External Links
UniProt Q5U913
EMBL AY773079
ProteinModelPortal Q5U913
SMR Q5U913
BioCyc MetaCyc:MONOMER-16086
GO GO:0016836
GO:0016491
GO:0055114
InterPro IPR002938
IPR003042
Pfam PF01494
PRINTS PR00420

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016491

oxidoreductase activity

PMID:15817470[1]

ECO:0000314

F

Based on table 1; for JadH, both UWM6 and 2,3-dehydro-UWM6 underwent 4a,12b-dehydration and C-12 monooxygenation and were converted to rabelomycin and dehydrorabelomycin, respectively. Rabelomycin remained unchanged. 3) In controls without supplemented enzymes, the substrates remained unchanged.

complete
CACAO 4979

GO:0016836

hydro-lyase activity

PMID:15817470[1]

ECO:0000314

F

Based on table 1: for JadH, both UWM6 and 2,3-dehydro-UWM6 underwent 4a,12b-dehydration and C-12 monooxygenation and were converted to rabelomycin and dehydrorabelomycin, respectively. Rabelomycin remained unchanged. 3) In controls without supplemented enzymes, the substrates remained unchanged.

complete
CACAO 4981

enables

GO:0016836

hydro-lyase activity

PMID:15817470[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

PMID:15817470[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016491

P

Seeded From UniProt

complete

enables

GO:0071949

FAD binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002938

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Chen, YH et al. (2005) Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase. J. Biol. Chem. 280 22508-14 PubMed GONUTS page