GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:17703433
| Citation |
De Mello, WC, Ferrario, CM and Jessup, JA (2007) Beneficial versus harmful effects of Angiotensin (1-7) on impulse propagation and cardiac arrhythmias in the failing heart. J Renin Angiotensin Aldosterone Syst 8:74-80 |
|---|---|
| Abstract |
The presence of Angiotensin (1-7) (Ang 1-7) and ACE 2 in the ventricle of cardiomyopathic hamsters as well as the influence of Ang (1-7) on membrane potential, impulse propagation and cardiac excitability were investigated. |
| Links |
PubMed Online version:10.3317/jraas.2007.015 |
| Keywords |
Angiotensin I/therapeutic use; Animals; Antihypertensive Agents/therapeutic use; Cardiomyopathies/drug therapy; Cardiomyopathies/pathology; Cardiomyopathies/physiopathology; Cricetinae; Disease Models, Animal; Heart/drug effects; Heart/physiopathology; Heart Rate/drug effects; Immunohistochemistry; Membrane Potentials/drug effects; Membrane Potentials/physiology; Myocardium/pathology; Peptide Fragments/therapeutic use; Sodium Channels/drug effects |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0017080: sodium channel regulator activity |
ECO:0000315: mutant phenotype evidence used in manual assertion |
F |
occurs_in:(CL:0000746) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1902632: positive regulation of membrane hyperpolarization |
ECO:0000315: mutant phenotype evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
Notes
See also
References
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