HAEIN:NADR

Species (Taxon ID)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd). (71421)
Gene Name(s)	nadR
Protein Name(s)	Bifunctional NAD biosynthesis protein NadR Nicotinamide mononucleotide adenylyltransferase NMN adenylyltransferase NMN-AT NMNAT Nicotinamide ribonucleotide adenylyltransferase Nicotinamide-nucleotide adenylyltransferase Ribosylnicotinamide kinase RNK Nicotinamide riboside kinase NRK NmR-K
External Links
UniProt	P44308
EMBL	L42023
PIR	D64091
RefSeq	NP_438922.1
PDB	1LW7
PDBsum	1LW7
ProteinModelPortal	P44308
SMR	P44308
STRING	71421.HI0763
TCDB	4.B.1.1.2
EnsemblBacteria	AAC22421
GeneID	950800
KEGG	hin:HI0763
PATRIC	20190177
eggNOG	COG3172
KO	K06211
OMA	QIRQDPF
OrthoDB	EOG6P06X5
PhylomeDB	P44308
BioCyc	MetaCyc:MONOMER-8322
UniPathway	UPA00253 UPA00253
EvolutionaryTrace	P44308
Proteomes	UP000000579
GO	GO:0005737 GO:0005886 GO:0005524 GO:0003677 GO:0000309 GO:0050262 GO:0009435 GO:0045892 GO:0006810
Gene3D	3.40.50.300 3.40.50.620
InterPro	IPR016429 IPR004821 IPR006417 IPR027417 IPR014729
PIRSF	PIRSF004776
SUPFAM	SSF52540
TIGRFAMs	TIGR00125 TIGR01526

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	PMID:15968050	ECO:0000315			F		In Figure 1, lanes 3 and 4, have had the RNK domain of NadR deleted. These lanes show no in vivo NAD+ synthesis.	complete
enables	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG11335 PANTHER:PTN002206349 UniProtKB:P44308	F		Seeded From UniProt	complete
enables	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006417	F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004821	F		Seeded From UniProt	complete
involved_in	GO:0009058	biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004821	P		Seeded From UniProt	complete
involved_in	GO:0009435	NAD biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006417	P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016429	P		Seeded From UniProt	complete
enables	GO:0050262	ribosylnicotinamide kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.1.22	F		Seeded From UniProt	complete
enables	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.7.1	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	P		Seeded From UniProt	complete
involved_in	GO:0019363	pyridine nucleotide biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0662	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	F		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
involved_in	GO:0009435	NAD biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00253	P		Seeded From UniProt	complete
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