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ECOLI:LPLA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | lplA (synonyms: yjjF) | |
| Protein Name(s) | Lipoate-protein ligase A
Lipoate--protein ligase | |
| External Links | ||
| UniProt | P32099 | |
| EMBL | L27665 U14003 U00096 AP009048 X03046 | |
| PIR | A54035 | |
| RefSeq | NP_418803.1 YP_492516.1 | |
| PDB | 1X2G 1X2H 3A7A 3A7R 4TVW 4TVY | |
| PDBsum | 1X2G 1X2H 3A7A 3A7R 4TVW 4TVY | |
| ProteinModelPortal | P32099 | |
| SMR | P32099 | |
| DIP | DIP-10119N | |
| IntAct | P32099 | |
| MINT | MINT-1288545 | |
| STRING | 511145.b4386 | |
| PaxDb | P32099 | |
| PRIDE | P32099 | |
| EnsemblBacteria | AAC77339 BAE78375 | |
| GeneID | 12933793 944865 | |
| KEGG | ecj:Y75_p4270 eco:b4386 | |
| PATRIC | 32124388 | |
| EchoBASE | EB1744 | |
| EcoGene | EG11796 | |
| eggNOG | COG0095 | |
| HOGENOM | HOG000260594 | |
| InParanoid | P32099 | |
| KO | K03800 | |
| OMA | WRNAETV | |
| OrthoDB | EOG6038ZS | |
| PhylomeDB | P32099 | |
| BioCyc | EcoCyc:EG11796-MONOMER ECOL316407:JW4349-MONOMER MetaCyc:EG11796-MONOMER | |
| UniPathway | UPA00537 UPA00537 | |
| EvolutionaryTrace | P32099 | |
| PRO | PR:P32099 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P32099 | |
| GO | GO:0005737 GO:0005524 GO:0016979 GO:0016740 GO:0018055 GO:0009249 | |
| HAMAP | MF_01602 | |
| InterPro | IPR004143 IPR023741 IPR019491 IPR004562 | |
| Pfam | PF03099 PF10437 | |
| TIGRFAMs | TIGR00545 | |
| PROSITE | PS51733 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016979 |
lipoate-protein ligase activity |
ECO:0000314 |
F |
Figure 2 shows a defect in the accumulation of 36s-lipoyl proteins when lacking the lplA gene demonstrating lipoate-protein ligase activity. |
complete | |||||
|
enables |
GO:0017118 |
lipoyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009249 |
protein lipoylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016979 |
lipoate-protein ligase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11796 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002288949 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016979 |
lipoate-protein ligase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016979 |
lipoate-protein ligase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009249 |
protein lipoylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006464 |
cellular protein modification process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009249 |
protein lipoylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016979 |
lipoate-protein ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016979 |
lipoate-protein ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000079207 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000079207 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009249 |
protein lipoylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000079207 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016874 |
ligase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Morris, TW et al. (1994) Identification of the gene encoding lipoate-protein ligase A of Escherichia coli. Molecular cloning and characterization of the lplA gene and gene product. J. Biol. Chem. 269 16091-100 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 McManus, E et al. (2006) Structure of a putative lipoate protein ligase from Thermoplasma acidophilum and the mechanism of target selection for post-translational modification. J. Mol. Biol. 356 625-37 PubMed GONUTS page
- ↑ 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
